Evidence map›Paper›PMID 34791604›Full record

ArticleJournal of endocrinological investigation2022

Delphi consensus on the diagnosis and treatment of patients with short stature in Spain: GROW-SENS study.

R Corripio-Collado, C Fernández-Ramos, I González-Casado, F Moreno-Macián, J-P López-Siguero, J-I Labarta-Aizpún

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

R Corripio-Collado *Paediatric Endocrinology Unit, Hospital Universitario Parc Taulí, Sabadell, Barcelona, Spain.ORCID http://orcid.org/0000-0003-3344-8269
C Fernández-Ramos *Paediatric Endocrinology Unit, Hospital Universitario Basurto, Bilbao, Spain.ORCID http://orcid.org/0000-0003-3740-4247
I González-Casado *Pediatric Endocrinology Deparment, Hospital Universitario La Paz, Madrid, Spain.ORCID http://orcid.org/0000-0001-7447-2914
F Moreno-Macián *Paediatric Endocrinology Unit, Hospital Universitario y Politécnico La Fe, Valencia, Spain.ORCID http://orcid.org/0000-0002-1240-0496
J-P López-Siguero *Paediatric Endocrinology Unit, Hospital Regional Universitario de Málaga, Instituto de Investigación de Málaga (IBIMA), Malaga, Spain.ORCID http://orcid.org/0000-0001-9282-9139
J-I Labarta-Aizpún *Paediatric Endocrinology Unit, Paediatric Department., Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria de Aragón, Zaragoza, Spain. jilabarta@salud.aragon.es.ORCID http://orcid.org/0000-0002-2319-5096
Hospital de Basurto · ESHospital Regional Universitario de Málaga · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario La Paz · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify consensus aspects related to the diagnosis, monitoring, and treatment of short stature in children to promote excellence in clinical practice.

methodsDelphi consensus organised in three rounds completed by 36 paediatric endocrinologists. The questionnaire consisted of 26 topics grouped into: (1) diagnosis; (2) monitoring of the small-for-gestational-age (SGA) patient; (3) growth hormone treatment; and (4) treatment adherence. For each topic, different questions or statements were proposed.

resultsAfter three rounds, consensus was reached on 16 of the 26 topics. The main agreements were: (1) diagnosis tests considered as a priority in Primary Care were complete blood count, biochemistry, thyroid profile, and coeliac disease screening. The genetic test with the greatest diagnostic value was karyotyping. The main criterion for initiating a diagnostic study was prediction of adult stature 2 standard deviations below the target height; (2) the main criterion for initiating treatment in SGA patients was the previous growth pattern and mean parental stature; (3) the main criterion for response to treatment was a significant increase in growth velocity and the most important parameter to monitor adverse events was carbohydrate metabolism; (4) the main attitude towards non-responding patients is to check their treatment adherence with recording devices. The most important criterion for choosing the delivery device was its technical characteristics.

conclusionsThis study shows the different degrees of consensus among paediatric endocrinologists in Spain concerning the diagnosis and treatment of short stature, which enables the identification of research areas to optimise the management of such patients.

Indexed as

DwarfismConsensusDelphi TechniqueFetal Growth RetardationHumansSpainSurveys and QuestionnairesAdherenceDelphiDiagnosisGrowth hormoneMonitoringShort stature

Identifiers

PMID34791604
PMCPMC8918130
OpenAlexW3212741454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.