ArticleJournal of general internal medicine2022
Evidence-Based Care for People with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.
Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Pooled it
- Interventions for the management of long covid (post-covid condition): living systematic review.BMJ (Clinical research ed.) · 2024Pooled it
- Fatigue severity and avoidance among individuals with chronic disease: A meta-analysis.Journal of psychosomatic research · 2022Pooled it
- Making recovery conceivable: perspectives from healthcare professionals using psychologically and behaviourally informed approaches to chronic fatigue syndrome.International journal of qualitative studies on health and well-being · 2026Article
- Managing Anxiety and Depression Symptoms in Long COVID.American family physician · 2026Article
- Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management.Journal of translational medicine · 2025Review
- The PACE Trial's GET Manual for Therapists Exposes the Fixed Incremental Nature of Graded Exercise Therapy for ME/CFS.Life (Basel, Switzerland) · 2025Article
- Chronic inflammatory response syndrome: a review of the evidence of clinical efficacy of treatment.Annals of medicine and surgery (2012) · 2024Review
- A pilot randomized controlled trial of a telemedicine psychosocial intervention to improve symptom management in adults with long COVID: the COPE study protocol.Pilot and feasibility studies · 2024Article
- Acquiring a new understanding of illness and agency: a narrative study of recovering from chronic fatigue syndrome.International journal of qualitative studies on health and well-being · 2023Article
- Chronic fatigue syndromes: real illnesses that people can recover from.Scandinavian journal of primary health care · 2023Article
- Evidence-Based Care for People with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.Journal of general internal medicine · 2022Article
- Bias in Exercise Trials for ME/CFS: the Importance of Objective Outcomes and Long-term Follow-up.Journal of general internal medicine · 2022Article
- Evidence-Based Care for People with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.Journal of general internal medicine · 2022Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Chronic fatigue syndrome (CFS), sometimes referred to as myalgic encephalomyelitis (ME) and often as CFS/ME, is an illness characterized by disabling fatigue and other symptoms, typically worsened by activity. The main evidence-based treatments are rehabilitative in nature and include specific types of cognitive behavior therapy (CBT) and graded exercise therapy (GET). In this article, we briefly review the evidence for their safety and effectiveness and propose that much of the controversy about them arises from misunderstandings about their nature and delivery. In particular, we emphasize that successful rehabilitation from CFS/ME does not indicate that the illness is not real. We recommend that rehabilitative treatment always be preceded by a thorough clinical assessment and delivered by appropriately trained therapists working in close collaboration with the patient. We conclude that properly applied rehabilitative treatments offer the best hope of safely improving fatigue and function for patients with CFS/ME. However, we also recognize the need for more research into the treatment of this neglected condition, especially for those most severely disabled by it.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.