Evidence map›Paper›PMID 34791560›Full record

ArticleBulletin of experimental biology and medicine2021

Long-Term Persistence of Increased Number of γH2AX

T M Blokhinа, E I Yashkina, A G Belyaeva, A A Perevezentsev, A S Shtemberg, A N Osipov

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

T M BlokhinаA. I. Burnasyan Federal Medical Biophysical Center, Federal Medical-Biological Agency of Russia, Moscow, Russia.
E I YashkinaA. I. Burnasyan Federal Medical Biophysical Center, Federal Medical-Biological Agency of Russia, Moscow, Russia.
A G BelyaevaInstitute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
A A PerevezentsevInstitute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
A S ShtembergInstitute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
A N OsipovA. I. Burnasyan Federal Medical Biophysical Center, Federal Medical-Biological Agency of Russia, Moscow, Russia. andreyan.osipov@gmail.com.
Institute of Biomedical Problems · RUSemenov Institute of Chemical Physics · RUFederal Medical-Biological Agency · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the influence of ionizing radiation and hypogravity as negative factors of space flights on DNA damage in peripheral blood lymphocytes of rhesus monkeys at different times after exposure (from 1 to 446 days). The proportion of cells with high numbers of DNA double-strand breaks (DSB), positive for the surrogate DSB marker-protein γH2AX, was monitored using flow cytometry. Some animals were exposed to 7-day antiorthostatic hypokinesia simulating hypogravity, the others to a combined effect of antiorthostatic hypokinesia, whole-body γ-irradiation (2.34 cGy/h, dose 1 Gy), and irradiation of the head with

Indexed as

Radiation, IonizingSpace FlightAnimalsDNA Breaks, Double-StrandedFlow CytometryHistonesHypogravityHypokinesiaLymphocytesMacaca mulattaMaleWhole-Body IrradiationHistoneshypogravityionizing radiationlymphocytesmonkeyγH2AX

Identifiers

PMID34791560
OpenAlexW3189261723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.