Evidence map›Paper›PMID 34791536›Full record

ReviewVirchows Archiv : an international journal of pathology2022

Artificial intelligence applied to breast pathology.

Mustafa Yousif, Paul J van Diest, Arvydas Laurinavicius, David Rimm, Jeroen van der Laak, Anant Madabhushi, Stuart Schnitt, Liron Pantanowitz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
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  5. Article
  6. Review
  7. Article
  8. AI-Powered Microscopic Diagnostic Techniques forJournal of dentistry (Shiraz, Iran) · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mustafa YousifDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA. Yousif.mustafa@outlook.com.ORCID http://orcid.org/0000-0002-4785-8579
Paul J van DiestDepartment of Pathology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Arvydas LaurinaviciusDepartment of Pathology, Pharmacology and Forensic Medicine, Faculty of Medicine, Vilnius University, and National Center of Pathology, Affiliate of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.
David RimmDepartment of Pathology, Yale University School of Medicine, New Haven, CT, USA.
Jeroen van der LaakDepartment of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Anant MadabhushiDepartment of Biomedical Engineering, Case Western Reserve University, and Louis Stokes Cleveland Veterans Administration Medical Center, Cleveland, OH, USA.
Stuart SchnittDepartment of Pathology, Brigham and Women's Hospital and Harvard Medical School, Breast Oncology Program, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Liron PantanowitzDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The convergence of digital pathology and computer vision is increasingly enabling computers to perform tasks performed by humans. As a result, artificial intelligence (AI) is having an astoundingly positive effect on the field of pathology, including breast pathology. Research using machine learning and the development of algorithms that learn patterns from labeled digital data based on "deep learning" neural networks and feature-engineered approaches to analyze histology images have recently provided promising results. Thus far, image analysis and more complex AI-based tools have demonstrated excellent success performing tasks such as the quantification of breast biomarkers and Ki67, mitosis detection, lymph node metastasis recognition, tissue segmentation for diagnosing breast carcinoma, prognostication, computational assessment of tumor-infiltrating lymphocytes, and prediction of molecular expression as well as treatment response and benefit of therapy from routine H&E images. This review critically examines the literature regarding these applications of AI in the area of breast pathology.

Indexed as

Artificial IntelligenceBreast NeoplasmsAlgorithmsBreastFemaleHumansMachine LearningNeural Networks, ComputerArtificial intelligenceBreastBreast cancerComputational pathologyConvolutional neural networkDeep learningHandcrafted featuresMachine learningQuantitative image analysis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.