Evidence map›Paper›PMID 34791428›Full record

ArticleNeuro-oncology2022

Consensus core clinical data elements for meningiomas (v2021.1).

Farshad Nassiri, Justin Z Wang, Karolyn Au, Jill Barnholtz-Sloan, Michael D Jenkinson, Kate Drummond, Yueren Zhou, James M Snyder, Priscilla Brastianos, Thomas Santarius and 8 more

Abstract readConsensus Statement
In one paragraph

Article in Neuro-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Meningioma recurrence: Time for an online prediction tool?Surgical neurology international · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Farshad NassiriMacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Justin Z WangMacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-8998-7443
Karolyn AuDivision of Neurosurgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Jill Barnholtz-SloanCase Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA.
Michael D JenkinsonDepartment of Neurosurgery, University of Liverpool, Liverpool, UK.
Kate DrummondDepartment of Neurosurgery, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Yueren ZhouDepartment of Biostatistics, Henry Ford Health System, Detroit, Michigan, USA.
James M SnyderDepartment of Neurology, Henry Ford Health System, Detroit, Michigan, USA.
Priscilla BrastianosDana Farber/Harvard Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Thomas SantariusDepartment of Neurosurgery, Cambridge University Hospitals, Cambridge, UK.
Suganth SuppiahMacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Laila PoissonDepartment of Biostatistics, Henry Ford Health System, Detroit, Michigan, USA.
Francesco GaillardDepartment of Radiology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Mark RosenthalDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Timothy KaufmannDepartment of Radiology, The Mayo Clinic, Rochester, Minnesota, USA.
Derek S TsangPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Kenneth AldapeNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Gelareh ZadehMacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Funding

Development and validation of a predictor of meningioma recurrenceZIABC011847 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ALDAPE, KENNETH · 2018 to 2025
$5.9M
CIHR
6 · The paper itself

Abstract

backgroundWith increasing molecular analyses of meningiomas, there is a need to harmonize language used to capture clinical data across centers to ensure that molecular alterations are appropriately linked to clinical variables of interest. Here the International Consortium on Meningiomas presents a set of core and supplemental meningioma-specific common data elements (CDEs) to facilitate comparative and pooled analyses.

methodsThe generation of CDEs followed the 4-phase process similar to other National Institute of Neurological Disorders and Stroke (NINDS) CDE projects: discovery, internal validation, external validation, and distribution.

resultsThe CDEs were organized into patient- and tumor-level modules. In total, 17 core CDEs (10 patient level and 7 tumor level) as well as 14 supplemental CDEs (7 patient level and 7 tumor level) were defined and described. These CDEs are now made publicly available for dissemination and adoption.

conclusionsCDEs provide a framework for discussion in the neuro-oncology community that will facilitate data-sharing for collaborative research projects and aid in developing a common language for comparative and pooled analyses. The meningioma-specific CDEs presented here are intended to be dynamic parameters that evolve with time and The Consortium welcomes international feedback for further refinement and implementation of these CDEs.

Indexed as

Biomedical ResearchCommon Data ElementsMeningeal NeoplasmsMeningiomaHumansNational Institute of Neurological Disorders and Stroke (U.S.)United Statesclinical trialsconsensuscore data elementsmeningiomaretrospective studies

Identifiers

PMID34791428
PMCPMC9071284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.