Trial reportThe British journal of surgery2021
A randomized clinical trial comparing early patient-reported pain after open anterior mesh repair versus totally extraperitoneal repair of inguinal hernia.
Trial report in The British journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03566433 (Early Postoperative Pain After Totally Extraperitoneal Endoscopic Technique), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Postoperative Pain After Totally Extraperitoneal Endoscopic Technique (TEP) vs. Lichtenstein Hernioplasty in Inguinal Hernia Repair: a Prospective Randomized Multi-center Study
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Comparison of totally extraperitoneal versus Lichtenstein operation under local or general anesthesia for inguinal hernia: a meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Laparoscopic approach in emergency for the treatment of acute incarcerated groin hernia: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- Laparoscopic inguinal hernia repair with self-fixated meshes: a randomized controlled trial.Surgical endoscopy · 2025Trial
- Beyond acronyms: a domain-based structural analysis of abdominal wall hernia repair techniques in the contemporary literature.Surgical endoscopy · 2026Article
- Short-term clinical outcomes of laparoscopic trans-abdominal pre-peritoneal repair using Parietex™ Lap.ProGrip™: a 10-year retrospective study.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- How Reproducible Are Abdominal Wall Surgical Techniques? A Methodological Assessment of Technical Reporting in the Contemporary Literature.Journal of abdominal wall surgery : JAWS · 2026Article
- Two-port (single incision plus one port) versus single-port laparoscopic totally extraperitoneal repair for inguinal hernia: a retrospective comparative study.Updates in surgery · 2024Article
- Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.World journal of emergency surgery : WJES · 2023Article
- Laparoscopic vs. Open Approach in Emergent Inguinal Hernia: Our Experience and Review of Literature.Journal of abdominal wall surgery : JAWS · 2023Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis was a prospective, multicentre, non-blinded, randomized clinical trial involving two parallel groups of patients.
methodsAdult patients with symptomatic unilateral primary inguinal hernia were included in this study. Patients were enrolled and treated in five Finnish hospitals. Eligible patients were randomized by use of a computer-based program to receiving either open anterior repair (modified Lichtenstein) with glue mesh fixation or totally extraperitoneal (TEP) repair. The primary aims were to compare 30-day patient-reported pain scores and return to work after surgery between the two groups.
resultsA total of 202 patients were randomized: 98 patients to TEP repair and 104 patients to open repair. All randomized patients received their allocated treatment. A total of 86 patients (88 per cent) in the TEP group and 94 patients (90 per cent) in the Lichtenstein group completed the 30-day follow-up. Patients experienced less early pain (P < 0.001) and used less analgesics after TEP repair, compared to those who had modified Lichtenstein repair. Two patients in the TEP group and five in the Lichtenstein group developed superficial wound infection (P = 0⋅446). Only one reoperation was performed in the Lichtenstein group due to haematoma.
conclusionTEP inguinal hernia repair is associated with less early postoperative pain compared to the open glue mesh fixation technique.
trial registrationNCT03566433 (http://www.clinicaltrials.gov).
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