ArticleEuropean journal of case reports in internal medicine2021
A Case of Severe COVID-19 in a Patient with Good's Syndrome.
Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Severe SARS-CoV-2 Infection and Campylobacter coli Bacteremia in a Patient With Good's Syndrome.Cureus · 2025Article
- Long COVID-19 leading to Good's syndrome diagnosis: A clinical case-report and literature review.Clinical case reports · 2024Article
- Human autoantibodies neutralizing type I IFNs: From 1981 to 2023.Immunological reviews · 2024Review
- Clinical and genomic evaluations of a persistent fatal SARS-CoV-2 infection in a goods syndrome patient: a case report.BMC infectious diseases · 2024Article
- Good's syndrome and COVID-19: case report and literature review.Mediastinum (Hong Kong, China) · 2023Article
- COVID-19 and Inborn Errors of Immunity.Physiology (Bethesda, Md.) · 2022Review
- [Patient with Good's syndrome and COVID-19. Report of a clinical case].Revista medica del Instituto Mexicano del Seguro Social · 2022Article
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Authors and funding
5 authors.
Funding
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Abstract
Good's syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the clinical suspicion of Good's syndrome. The mortality rate associated with infectious complications is high. Thus, although it is rare, the disease should be diagnosed early so that proper treatment can be started. Thymectomy and immunoglobulin replacement are the main therapeutic strategies. We describe the case of a patient with a history of thymoma and recurrent respiratory infections, with a late diagnosis of Good's syndrome in the context of severe organizing pneumonia secondary to COVID-19. LEARNING POINTS: Infection is the leading cause of mortality in patients with Good's syndrome.Early recognition of this rare disease and substitutive therapy with immunoglobulin may have an important impact on prognosis.Due to its rarity, data on Good's syndrome are scarce and its association with severe COVID-19 onset is still unclear.To the best of our knowledge, this is the fifth case report of COVID-19 in a patient with Good's syndrome, the third with a favourable outcome.
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