Evidence map›Paper›PMID 34790531›Full record

ArticleEndoscopy international open2021

Hybrid endoscopic mucosal resection and full-thickness resection for large colonic polyps harboring a small focus of invasive cancer: a case series.

Jamie S Chua, Hao Dang, Liselotte W Zwager, Nik Dekkers, James C H Hardwick, Alexandra M J Langers, Jolein van der Kraan, Lars E Perk, Barbara A J Bastiaansen, Jurjen J Boonstra and 1 more

Open access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jamie S ChuaDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Hao DangDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Liselotte W ZwagerDepartment of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Nik DekkersDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
James C H HardwickDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Alexandra M J LangersDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Jolein van der KraanDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Lars E PerkDepartment of Gastroenterology and Hepatology, Haaglanden Medical Center, the Hague, the Netherlands.
Barbara A J BastiaansenDepartment of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Jurjen J BoonstraDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Dutch eFTR Working Group
Leiden University Medical Center · NLAmsterdam University Medical Centers · NLMedisch Centrum Haaglanden · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic treatment of large laterally spreading tumors (LSTs) with a focus of submucosally invasive colorectal cancer (T1 CRC) can be challenging. We evaluated outcomes of a hybrid resection technique using piecemeal endoscopic mucosal resection (pEMR) and endoscopic full-thickness resection (eFTR) in patients with large colonic LSTs containing suspected T1 CRC. Six hybrid pEMR-eFTR procedures for T1 CRCs were registered in a nationwide eFTR registry between July 2015 and December 2019. In all cases, the invasive part of the lesion was successfully isolated with eFTR; with eFTR, histologically complete resection of the invasive part was achieved in 5 /6 patients (83.3 %). No adverse events occurred during or after the procedure. The median follow-up time was 10 months (range 6-27), with all patients having undergone ≥ 1 surveillance colonoscopy. One patient had a small adenomatous recurrence, which was removed endoscopically. In conclusion, hybrid pEMR-eFTR is a promising noninvasive treatment modality that seems feasible for a selected group of patients with large LSTs containing a small focus of T1 CRC.

Identifiers

PMID34790531
PMCPMC8589547
OpenAlexW3211463668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.