ArticleTherapeutic advances in neurological disorders2021
Surgical outcome and prognostic factors in spinal cord ependymoma: a single-center, long-term follow-up study.
Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical characteristics and prognostic factors of primary spinal subependymoma: a single-center cohort study and systematic review.Journal of neuro-oncology · 2025Pooled it
- Outcomes after surgical resection of spinal ependymomas: extent of resection, imaging phenotype, and survival.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Two Central Nervous System Tumors in One Catheter Lab: Time to Rethink Radiation Protection.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Preoperative risk stratification for long-term neurological status in spinal ependymoma: an MRI-centered nomogram.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Clinical Characteristics, Management, and Outcomes of Intramedullary Spinal Cord Ependymomas: A Systematic Review and Meta-Analysis.Spine surgery and related research · 2026Review
- Prognosis and strategies for reoperation in recurrent spinal tumors: an average 5-Year follow-up retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Outcomes in spinal ependymoma: A retrospective analysis of 38 patients.Surgical neurology international · 2026Article
- Intramedullary Ependymoma of the Cervicomedullary Junction: Gross Total Resection and Surgical Nuances in an Anatomically Rare Location.Cancer management and research · 2026Article
- Radiological analysis correlated with neurological outcomes following resection of myxopapillary ependymoma: patient series.Journal of neurosurgery. Case lessons · 2025Article
- Current Approach and Predictors of Clinical Outcomes in Adults With Spinal Ependymomas.Cureus · 2025Article
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- Neurological Outcome and Respiratory Insufficiency in Intramedullary Tumors of the Upper Cervical Spine.Medicina (Kaunas, Lithuania) · 2023Article
- Long-Term Outcomes after Incomplete Resection of Intramedullary Grade II Ependymomas: Is Adjuvant Radiotherapy Justified?Cancers · 2023Article
- Intramedullary spinal cord and filum tumours-long-term outcome: single institution case series.Acta neurochirurgica · 2022Article
- Spinal Meningioma Surgery through the Ages-Single-Center Experience over Three Decades.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSpinal cord ependymomas account for 3-6% of all central nervous system tumors and around 60% of all intramedullary tumors. The aim of this study was to analyze the neurological outcome after surgery and to determine prognostic factors for functional outcome. PATIENTS AND
methodsPatients treated surgically due to a spinal cord ependymoma between 1990 and 2018 were retrospectively included. Demographics, neurological symptoms, radiological parameters, histopathology, and neurological outcome (using McCormick Score [MCS]) were analyzed. Possible prognostic factors for neurological outcome were evaluated.
resultsIn total, 148 patients were included (76 males, 51.4%). The mean age was 46.7 ± 15.3 years. The median follow-up period was 6.8 ± 5.4 years. The prevalence was mostly in the lumbar spine (45.9%), followed by the thoracic spine (28.4%) and cervical spine (25.7%). Gross-total resection was achieved in 129 patients (87.2%). The recurrence rate was 8.1% and depended on the extent of tumor resection (
conclusionNeurological deterioration was seen in the majority of cervical and thoracic spine ependymomas. Postoperative improvement was less in thoracic cervical spine ependymomas compared with thoracic spine ependymomas. Poor preoperative status and especially tumor extension >2 vertebrae are predictors of poor neurological outcome (MCS >2).
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