Evidence map›Paper›PMID 34790196›Full record

ArticleFrontiers in immunology2021

DC-SIGN Mediates the Interaction Between Neutrophils and

Rafael Tiburcio, Léon Dimitri Melo, Sara Nunes, Ana Luísa Augusto Barbosa, Elaine Carvalho de Oliveira, Martha Suarez, Valéria M Borges, Natalia Tavares, Claudia Ida Brodskyn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Mechanisms and therapeutic potential of therapy-induced cellular senescence in radiotherapy- and chemotherapy-related alimentary tract mucositis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  2. Review
  3. Review
  4. Human Dendritic Cell Maturation Is Modulated byTropical medicine and infectious disease · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rafael TiburcioInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Léon Dimitri MeloInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Sara NunesInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Ana Luísa Augusto BarbosaInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Elaine Carvalho de OliveiraInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Martha SuarezInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Valéria M BorgesInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Natalia TavaresInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Claudia Ida BrodskynInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BRInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leishmaniasis is a neglected arthropod-borne disease that affects millions of people worldwide. Successful Objective: We sought to investigate how PMNs and infected DCs interact in an Material and Methods: Briefly, human PMNs and DCs were purified from the peripheral blood of healthy donors. Next, PMNs were activated with fibronectin and subsequently co-cultured with Results: We observed that Conclusion: Our findings suggest that the engagement of direct contact between PMNs and

Indexed as

Cell Adhesion MoleculesCell DifferentiationCells, CulturedCoculture TechniquesDC-Specific ICAM-3 Grabbing NonintegrinDendritic CellsHumansLectins, C-TypeLeishmaniaLeishmaniasisNeutrophilsReceptors, Cell SurfaceTumor Necrosis Factor-alphaCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypeReceptors, Cell SurfaceTNF protein, humanTumor Necrosis Factor-alphaDC maturation markersDC-SIGNleishmaniasismonocyte-derived dendritic cellspolymorphonuclear cells

Identifiers

PMID34790196
PMCPMC8591281
OpenAlexW3210406264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.