Evidence map›Paper›PMID 34790095›Full record

ArticleFrontiers in molecular neuroscience2021

Glyoxalase 1 Confers Susceptibility to Schizophrenia: From Genetic Variants to Phenotypes of Neural Function.

Jingwen Yin, Guoda Ma, Shucun Luo, Xudong Luo, Bin He, Chunmei Liang, Xiang Zuo, Xusan Xu, Qing Chen, Susu Xiong and 14 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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  4. Association betweenFrontiers in endocrinology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 2 countries.

Jingwen YinDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Guoda MaInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Shucun LuoDepartment of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Xudong LuoDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Bin HeDepartment of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Chunmei LiangInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Xiang ZuoInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Xusan XuInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Qing ChenDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Susu XiongDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhi TanDepartment of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Jiawu FuInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Dong LvDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhun DaiDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Xia WenInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Dongjian ZhuDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Xiaoqing YeDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhixiong LinDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Juda LinDepartment of Psychiatry, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
You LiInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Wubiao ChenDepartment of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zebin LuoDepartment of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Keshen LiInstitute of Neurology, Guangdong Medical University, Zhanjiang, China.
Yajun WangMaternal and Children's Health Research Institute, Shunde Maternal and Children's Hospital, Guangdong Medical University, Foshan, China.
Guangdong Medical College · CNFirst Affiliated Hospital of Jinan University · CNFoshan Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research aimed to investigate the role of glyoxalase 1 (Glo-1) polymorphisms in the susceptibility of schizophrenia. Using the real-time polymerase chain reaction (PCR) and spectrophotometric assays technology, significant differences in Glo-1 messenger ribonucleic acid (mRNA) expression (

Indexed as

brain functionenzymatic activityeQTLGlo-1mRNA expressionpromoter activityrs1781735schizophrenia

Identifiers

PMID34790095
PMCPMC8592033
OpenAlexW3208327810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.