Evidence map›Paper›PMID 34790019›Full record

SynthesisWorld journal of gastroenterology2021

Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis.

Eszter Boros, Zoltán Sipos, Péter Hegyi, Brigitta Teutsch, Levente Frim, Szilárd Váncsa, Szabolcs Kiss, Fanni Dembrovszky, Eduard Oštarijaš, Andrew Shawyer and 1 more

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Eszter BorosInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Zoltán SiposInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Péter HegyiInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Brigitta TeutschInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Levente FrimInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Szilárd VáncsaInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Szabolcs KissInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Fanni DembrovszkyInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Eduard OštarijašInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary.
Andrew ShawyerDepartment of Interventional Radiology, University Hospitals Dorset NHS Foundation Trust, Bournemouth BH7 7DW, United Kingdom.
Bálint ErőssInstitute for Translational Medicine, University of Pecs, Medical School, Pécs 7624, Hungary. eross.balint@pte.hu.
University of Pecs · HUDorset HealthCare University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the improvement in the endoscopic hemostasis of non-variceal upper gastrointestinal bleeding (NVUGIB), rebleeding remains a major concern.

aimTo assess the role of prophylactic transcatheter arterial embolization (PTAE) added to successful hemostatic treatment among NVUGIB patients.

methodsWe searched three databases from inception through October 19

resultsWe included a total of 3 RCTs and 9 observational studies with a total of 1329 patients, with 486 in the intervention group. PTAE was associated with lower odds of rebleeding (OR = 0.48, 95%CI: 0.29-0.78). There was no difference in the 30-d mortality rates (OR = 0.82, 95%CI: 0.39-1.72) between the PTAE and control groups. Patients who underwent PTAE treatment had a lower chance for reintervention (OR = 0.48, 95%CI: 0.31-0.76) or rescue surgery (OR = 0.35, 95%CI: 0.14-0.92). The LOH and ICU stay was shorter in the PTAE group, but the difference was non-significant [WMD = -3.77, 95%CI: (-8.00)-0.45; WMD = -1.33, 95%CI: (-2.84)-0.18, respectively].

conclusionPTAE is associated with lower odds of rebleeding and any reintervention in NVUGIB. However, further RCTs are needed to have a higher level of evidence.

Indexed as

Embolization, TherapeuticHemostasis, EndoscopicUpper Gastrointestinal TractGastrointestinal HemorrhageHumansRecurrenceVascular Surgical ProceduresMeta-analysisNon-variceal upper gastrointestinal bleedingProphylactic transcatheter arterial embolizationRebleedingReinterventionReview

Identifiers

PMID34790019
PMCPMC8567479
OpenAlexW3209244184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.