ArticleNature2021
Herpesviruses assimilate kinesin to produce motorized viral particles.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 63 citations in OpenAlex.
- Article
- The antiviral GTPase MxB is packaged into virions and binds via its N-terminal domain to alphaherpesvirus capsids.PLoS pathogens · 2026Article
- HSV-1 strain H129 co-opts neuronal synaptic transmission machinery for its transsynaptic spread.Nature neuroscience · 2026Article
- Proximity labelling identifies proteins associated with HSV-2 pUL21 at early and late times after infection.PLoS pathogens · 2026Article
- From the Gut to the Brain: Microplastic-Associated Neurovascular Dysfunction and Implications for Stroke Risk.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Antagonistic co-evolution throughout the herpesvirus life cycle.Virus evolution · 2026Review
- Article
- Review
- HSV-1 virions and related particles: biogenesis and implications in the infection.Journal of virology · 2025Review
- Tethered release of the pseudorabies virus deubiquitinase from the capsid promotes enzymatic activity.Journal of virology · 2025Article
- The gE/gI complex is necessary for kinesin-1 recruitment during alphaherpesvirus egress from neurons.Journal of virology · 2025Article
- An updated review of HSV-1 infection-associated diseases and treatment, vaccine development, and vector therapy application.Virulence · 2024Review
- Understanding neurotropic enteric viruses: routes of infection and mechanisms of attenuation.Cellular and molecular life sciences : CMLS · 2024Review
- A review of HSV pathogenesis, vaccine development, and advanced applications.Molecular biomedicine · 2024Review
- Article
- Article
- Herpes simplex virus type-1 cVAC formation in neuronal cells is mediated by dynein motor function and glycoprotein retrieval from the plasma membrane.Journal of virology · 2024Article
- Models of Herpes Simplex Virus Latency.Viruses · 2024Review
- The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The host cytoskeleton: a key regulator of early HIV-1 infection.The FEBS journal · 2024Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Caitlin E Pegg *Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Sofia V Zaichick *Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ewa Bomba-WarczakDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Vladimir JovasevicDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-8963-6758
DongHo KimDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Himanshu KharkwalDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Duncan W WilsonDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Derek WalshDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-8756-4655
Patricia J SollarsSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE, USA.ORCID http://orcid.org/0000-0002-1731-0502
Gary E PickardSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE, USA.
Jeffrey N SavasDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-8173-5580
Gregory A SmithDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. g-smith3@northwestern.edu.ORCID http://orcid.org/0000-0001-9644-8472
Northwestern University · USAlbert Einstein College of Medicine · USUniversity of Nebraska–Lincoln · US
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9MWORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2MCELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1MAlpha-Herpesvirus Transport on AxonsR01AI056346 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SMITH, GREGORY ALLAN · 2004 to 2024
$6.8MNeurotropic herpesvirus envelopment and microtubule-mediated transportR01AI125244 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Gregory Allan Smith, DUNCAN W. WILSON · 2017 to 2026
$6.5MNuclear rotation and cellular reorganization during Cytomegalovirus infectionR01AI141470 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Derek Walsh · 2019 to 2026
$3.6MVirus-host interactions governing alpha-herpesvirus genome delivery and neuroinvasionR01AI148780 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PICKARD, GARY EDWARD, SAVAS, JEFFREY NICHOLAS · 2020 to 2024
$2.5MAndor Revolution XD Live Cell Imaging System with Photomanipulation LaserS10RR031680 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GELFAND, VLADIMIR I · 2011 to 2011
$437kAlpha-Herpevirus Transport in AxonsR56AI056346 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SMITH, GREGORY ALLAN · 2009 to 2009
$333kInvestigating the role of extremely long-lived mitochondrial proteins in mammalian neuronsF32NS106812 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BOMBA-WARCZAK, EWA KAROLINA · 2018 to 2019
$95kNCI NIH HHS P30 CA013330NCI NIH HHS P30 CA060553NCRR NIH HHS S10 RR031680NIAID NIH HHS R01 AI056346NIAID NIH HHS R01 AI125244NIAID NIH HHS R01 AI141470NIAID NIH HHS R01 AI148780NIAID NIH HHS R56 AI056346NIGMS NIH HHS T32 GM008061NINDS NIH HHS F32 NS106812
Abstract
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established
Indexed as
MovementVirus AssemblyAnimalsBiological TransportCapsidCell LineCell NucleusChlorocebus aethiopsEpithelial CellsHerpesvirus 1, HumanHerpesvirus 1, SuidHumansKinesinsNeuronsRabbitsSwineKinesins
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.