SynthesisScientific reports2021
The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06922552 (Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization), which is not on this map. Cited by 81 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization: A Randomized Clinical Trial
Who cites it
81 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Global prevalence of hypomineralised second primary molars: an updated systematic review with a meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Prevalence of molar-incisor hypomineralisation (MIH) in children in the Gulf Cooperation Council countries: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Prevalence and association of Molar Incisor Hypomineralization (MIH) in patients presenting dental fluorosis: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Prevalence of developmental defects of enamel in Brazil: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Effective anaesthesia when treating teeth affected by molar incisor hypomineralisation (MIH): a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Epidemiological trends in enamel hypomineralisation and molar-incisor hypomineralisation: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Is there a rise of prevalence for Molar Incisor Hypomineralization? A meta-analysis of published data.BMC oral health · 2024Pooled it
- A systematic review and meta-analysis on the association between CD36 rs1761667 polymorphism and cardiometabolic risk factors in adults.Scientific reports · 2022Pooled it
- Association between respiratory diseases and molar-incisor hypomineralization: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- "Evaluation of Silver Diamine Fluoride Modified Atraumatic Restorative Treatment (SMART) on hypomineralized first permanent molar"- a randomized controlled clinical study.BMC oral health · 2024Trial
- Are childhood diseases associated with Molar-Incisor Hypomineralization? - Results from an observational study.Clinical oral investigations · 2026Observational
- Association between molar-incisor hypomineralisation and occlusal alterations in children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Knowledge, Perception, and Clinical Experiences on Molar Incisor Hypomineralization Amongst Dental Professionals: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Non-invasive management strategies for molar-incisor hypomineralization (MIH) in children.The Cochrane database of systematic reviews · 2026Article
- Human Enamel Formation: A Scoping Review for Oral Health Professionals.Dentistry journal · 2026Review
- Uncovering the hidden costs of Molar Incisor Hypomineralization (MIH): the impact of later diagnosis on clinical outcomes and financial cost.Odontology · 2026Article
- Comparative evaluation of remineralization agents in severe enamel hypomineralization using a porcine enamel model.BMC oral health · 2026Article
- Effect of Deproteinization on the Clinical Success of Composite Restorations in Molars Affected by Molar-Incisor Hypomineralization.Children (Basel, Switzerland) · 2026Article
- High prevalence of molar-incisor hypomineralisation in sickle cell disease children and the association with haematologic profile: a retrospective cohort study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molar-Incisor Hypomineralization (MIH) is a qualitative defect of enamel of unknown etiology, affecting one or more permanent molars and may include incisors. This condition is a clinical challenge and its prevalence is still uncertain given the recent increase in research. Thus, we aimed to comprehensively estimate the overall prevalence of MIH and associated characteristics. This systematic review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). We searched articles using PubMed, MEDLINE, CENTRAL, Web of Science, SciELO, LILACS and TRIP databases, until July 2021. Heterogeneity and publication bias were computed via I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.