ArticleScientific reports2021
Light-stimulus intensity modulates startle reflex habituation in larval zebrafish.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Negative-Valence Neurons in the Larval Zebrafish Pallium.bioRxiv : the preprint server for biology · 2026Article
- Plating larval zebrafish prior to the day of experimentation has no impact on spontaneous swimming and startle responses.MethodsX · 2025Article
- Tensor analysis of animal behavior by matricization and feature selection.Computers in biology and medicine · 2025Article
- Review
- Stunned by a Heatwave: Experimental Heatwaves Alter Juvenile Responsiveness to the Threat of Predation.Ecology and evolution · 2025Article
- High throughput machine learning pipeline to characterize larval zebrafish motor behavior.PloS one · 2025Article
- Effects of environmental colours in virtual reality: Physiological arousal affected by lightness and hue.Royal Society open science · 2023Article
- Article
- Biomechanical induction of mild brain trauma in larval zebrafish: effects on visual startle reflex habituation.Brain communications · 2023Article
- Individual differences and knockout in zebrafish reveal similar cognitive effects of BDNF between teleosts and mammals.Proceedings. Biological sciences · 2022Article
- Comparison of anxiety-like and social behaviour in medaka and zebrafish.Scientific reports · 2022Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The startle reflex in larval zebrafish describes a C-bend of the body occurring in response to sudden, unexpected, stimuli of different sensory modalities. Alterations in the startle reflex habituation (SRH) have been reported in various human and animal models of neurological and psychiatric conditions and are hence considered an important behavioural marker of neurophysiological function. The amplitude, offset and decay constant of the auditory SRH in larval zebrafish have recently been characterised, revealing that the measures are affected by variation in vibratory frequency, intensity, and interstimulus-interval. Currently, no study provides a model-based analysis of the effect of physical properties of light stimuli on the visual SRH. This study assessed the effect of incremental light-stimulus intensity on the SRH of larval zebrafish through a repeated-measures design. Their total locomotor responses were normalised for the time factor, based on the behaviour of a (non-stimulated) control group. A linear regression indicated that light intensity positively predicts locomotor responses due to larger SRH decay constants and offsets. The conclusions of this study provide important insights as to the effect of light properties on the SRH in larval zebrafish. Our methodology and findings constitute a relevant reference framework for further investigation in translational neurophysiological research.
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