Evidence map›Paper›PMID 34789723›Full record

ArticleNature communications2021

Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry.

Che-Hang Yu, Jeffrey N Stirman, Yiyi Yu, Riichiro Hira, Spencer L Smith

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 143 citations in OpenAlex.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Che-Hang Yu *Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA.
Jeffrey N Stirman *LifeCanvas Technologies, Cambridge, MA, USA.
Yiyi YuDepartment of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA.ORCID 0000-0003-1053-413X
Riichiro HiraDepartment of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA.ORCID 0000-0002-8719-4498
Spencer L SmithDepartment of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA. sls@ucsb.edu.ORCID 0000-0002-2021-7034
University of California, Santa Barbara · US

Funding

Modulation of dendritic spiking in vivoR01NS091335 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRENMAN, JAY, SMITH, SPENCER LAVERE · 2015 to 2020
$2.0M
Development and function of higher visual areas in miceR01EY024294 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SPENCER LAVERE · 2015 to 2019
$1.7M
NEI NIH HHS R01 EY024294NINDS NIH HHS R01 NS091335
6 · The paper itself

Abstract

Imaging the activity of neurons that are widely distributed across brain regions deep in scattering tissue at high speed remains challenging. Here, we introduce an open-source system with Dual Independent Enhanced Scan Engines for Large field-of-view Two-Photon imaging (Diesel2p). Combining optical design, adaptive optics, and temporal multiplexing, the system offers subcellular resolution over a large field-of-view of ~25 mm

Indexed as

BrainCalciumEquipment DesignMicroscopy, Fluorescence, MultiphotonNerve NetNeuronsOptical ImagingCalcium

Identifiers

PMID34789723
PMCPMC8599518
OpenAlexW3213642587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.