Evidence map›Paper›PMID 34789566›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Synergistic regulation of nonbinary molecular switches by protonation and light.

Xin Zhang, Yu-Dong Yang, Zhi-Hao Lu, Li-Jin Xu, Jonathan L Sessler, Han-Yuan Gong

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Synergistic regulation of metal-organic cage architectures via temperature- and solvent-driven atropisomerism.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Profile of Jonathan L. Sessler.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin ZhangDepartment of Chemistry, Renmin University of China, Beijing 100872, People's Republic of China.
Yu-Dong YangCollege of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China.
Zhi-Hao LuBeijing Engineering Research Center of Protein and Functional Peptides, China National Research Institute of Food and Fermentation Industries Co. Ltd., Beijing 100015, People's Republic of China.
Li-Jin XuDepartment of Chemistry, Renmin University of China, Beijing 100872, People's Republic of China; 20050062@ruc.edu.cn sessler@cm.utexas.edu hanyuangong@bnu.edu.cn.
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712-1224; 20050062@ruc.edu.cn sessler@cm.utexas.edu hanyuangong@bnu.edu.cn.ORCID 0000-0002-9576-1325
Han-Yuan GongCollege of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China; 20050062@ruc.edu.cn sessler@cm.utexas.edu hanyuangong@bnu.edu.cn.ORCID 0000-0003-4168-7657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a molecular switching ensemble whose states may be regulated in synergistic fashion by both protonation and photoirradiation. This allows hierarchical control in both a kinetic and thermodynamic sense. These pseudorotaxane-based molecular devices exploit the so-called Texas-sized molecular box (cyclo[2]-(2,6-di(1H-imidazol-1-yl)pyridine)[2](1,4-dimethylenebenzene); 1

Indexed as

chemical switchesimidazolium macrocycleskinetics and thermodynamicslight-driven conversionsprotonation effects

Identifiers

PMID34789566
PMCPMC8617463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.