Evidence map›Paper›PMID 34789490›Full record

ArticleBMJ open2021

Cohort profile: the Mâncio Lima cohort study of urban malaria in Amazonian Brazil.

Igor C Johansen, Priscila T Rodrigues, Juliana Tonini, Joseph Vinetz, Marcia C Castro, Marcelo U Ferreira

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03689036 (Transmission Dynamics of Residual and Re-emerging Malaria in the Amazon), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03689036 unknown statusnot on this map

Transmission Dynamics of Residual and Re-emerging Malaria in the Amazon: Defining a Roadmap to Malaria Elimination_Part A: Acre, Brazil

TypeobservationalSponsorOswaldo Cruz FoundationRan2018 to 2024Enrolled2,000ConditionsMalaria
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Igor C Johansen *Parasitology, University of Sao Paulo, Sao Paulo, Brazil.
Priscila T Rodrigues *Parasitology, University of Sao Paulo, Sao Paulo, Brazil.
Juliana ToniniParasitology, University of Sao Paulo, Sao Paulo, Brazil.
Joseph VinetzInternal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Marcia C CastroGlobal Health and Population, Harvard School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0003-4606-2795
Marcelo U FerreiraParasitology, University of Sao Paulo, Sao Paulo, Brazil muferrei@usp.br.ORCID 0000-0002-5293-9090
Universidade de São Paulo · BRHarvard Global Health Institute · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI GAZZINELLI, RICARDO TOSTES · 2010 to 2023
$20.1M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS U19 AI089681
6 · The paper itself

Abstract

purposeThis population-based open cohort study aims to investigate biological and sociodemographic drivers of malaria transmission in the main urban hotspot of Amazonian Brazil.

participantsNearly 20% of the households in the northwestern town of Mâncio Lima were randomly selected and 2690 participants were enrolled since April 2018. Sociodemographic, housing quality, occupational, behavioural and morbidity information and travel histories were collected during consecutive study visits. Blood samples from participants>3 months old were used for malaria diagnosis and human genetic studies; samples from participants with laboratory-confirmed malaria have been cryopreserved for genetic and phenotypic characterisation of parasites. Serology was introduced in 2020 to measure the prevalence and longevity of SARS-CoV-2 IgG antibodies. FINDINGS TO DATE: Malaria prevalence rates were low (up to 1.0% for FUTURE PLANS: Two follow-up visits, with similar study protocols, are planned in 2021. We aim to identify high-risk individuals that fuel onwards malaria transmission and represent a priority target for more intensive and effective control interventions. TRIAL REGISTRATION NUMBER: NCT03689036.

Indexed as

COVID-19MalariaMalaria, FalciparumMalaria, VivaxAdultBrazilCohort StudiesCross-Sectional StudiesHumansInfantMalePrevalenceSARS-CoV-2epidemiologyparasitology

Identifiers

PMID34789490
PMCPMC8727682
OpenAlexW3214503565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.