Evidence map›Paper›PMID 34789305›Full record

ArticleCritical care (London, England)2021

In the eye of the storm: impact of COVID-19 pandemic on admission patterns to paediatric intensive care units in the UK and Eire.

Hari Krishnan Kanthimathinathan, Hannah Buckley, Peter J Davis, Richard G Feltbower, Caroline Lamming, Lee Norman, Lyn Palmer, Mark J Peters, Adrian Plunkett, Padmanabhan Ramnarayan and 2 more

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  8. The care of critically ill adults with COVID-19 in Ontario pediatric intensive care units.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
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  13. Antibiotic Indications and Appropriateness in the Pediatric Intensive Care Unit: A 10-Center Point Prevalence Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Hari Krishnan KanthimathinathanPaediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Hannah BuckleyLeeds Institute for Data Analytics, University of Leeds, Leeds, UK.
Peter J DavisPaediatric Intensive Care Unit, Bristol Royal Hospital for Children, Bristol, UK.
Richard G FeltbowerLeeds Institute for Data Analytics, University of Leeds, Leeds, UK.
Caroline LammingDepartment of Health Sciences, George Davies Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Lee NormanLeeds Institute for Data Analytics, University of Leeds, Leeds, UK.
Lyn PalmerDepartment of Health Sciences, George Davies Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Mark J PetersPaediatric Intensive Care, Great Ormond Street Hospital NHS Foundation Trust, NIHR Biomedical Research Centre, London, UK.
Adrian PlunkettPaediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Padmanabhan RamnarayanChildren's Acute Transport Service, Great Ormond Street Hospital NHS Foundation Trust, NIHR Biomedical Centre, London, UK.
Barnaby R ScholefieldPaediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Elizabeth S DraperDepartment of Health Sciences, George Davies Centre, College of Life Sciences, University of Leicester, Leicester, UK. msn@leicester.ac.uk.ORCID 0000-0001-9340-8176
Birmingham Women’s and Children’s NHS Foundation Trust · GBUniversity of Leeds · GBUniversity of Leicester · GBBristol Royal Hospital for Children · GBGreat Ormond Street Hospital · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease-19 (COVID-19) pandemic had a relatively minimal direct impact on critical illness in children compared to adults. However, children and paediatric intensive care units (PICUs) were affected indirectly. We analysed the impact of the pandemic on PICU admission patterns and patient characteristics in the UK and Ireland.

methodsWe performed a retrospective cohort study of all admissions to PICUs in children < 18 years during Jan-Dec 2020, using data collected from 32 PICUs via a central database (PICANet). Admission patterns, case-mix, resource use, and outcomes were compared with the four preceding years (2016-2019) based on the date of admission.

resultsThere were 16,941 admissions in 2020 compared to an annual average of 20,643 (range 20,340-20,868) from 2016 to 2019. During 2020, there was a reduction in all PICU admissions (18%), unplanned admissions (20%), planned admissions (15%), and bed days (25%). There was a 41% reduction in respiratory admissions, and a 60% reduction in children admitted with bronchiolitis but an 84% increase in admissions for diabetic ketoacidosis during 2020 compared to the previous years. There were 420 admissions (2.4%) with either PIMS-TS or COVID-19 during 2020. Age and sex adjusted prevalence of unplanned PICU admission reduced from 79.7 (2016-2019) to 63.1 per 100,000 in 2020. Median probability of death [1.2 (0.5-3.4) vs. 1.2 (0.5-3.4) %], length of stay [2.3 (1.0-5.5) vs. 2.4 (1.0-5.7) days] and mortality rates [3.4 vs. 3.6%, (risk-adjusted OR 1.00 [0.91-1.11, p = 0.93])] were similar between 2016-2019 and 2020. There were 106 fewer in-PICU deaths in 2020 (n = 605) compared with 2016-2019 (n = 711).

conclusionsThe use of a high-quality international database allowed robust comparisons between admission data prior to and during the COVID-19 pandemic. A significant reduction in prevalence of unplanned admissions, respiratory diseases, and fewer child deaths in PICU observed may be related to the targeted COVID-19 public health interventions during the pandemic. However, analysis of wider and longer-term societal impact of the pandemic and public health interventions on physical and mental health of children is required.

Indexed as

PandemicsChildCOVID-19HumansIntensive Care Units, PediatricIrelandPatient AdmissionRetrospective StudiesUnited KingdomAdmission patternsCase mixCOVID19Paediatric intensive care unit

Identifiers

PMID34789305
PMCPMC8597872
OpenAlexW3214049404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.