Evidence map›Paper›PMID 34789288›Full record

ArticleJournal of nanobiotechnology2021

Rapidly liver-clearable rare-earth core-shell nanoprobe for dual-modal breast cancer imaging in the second near-infrared window.

Zhuxin Wei, Guangxin Duan, Baoxing Huang, Shanshan Qiu, Dandan Zhou, Jianfeng Zeng, Jiabin Cui, Chunhong Hu, Ximing Wang, Ling Wen and 1 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  4. Inhibiting concentration quenching in YbNature communications · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhuxin Wei *Department of Radiology, The First Affiliated Hospital of Soochow University, Institute of Medical Imaging, Soochow University, 188 Shizi Street, Suzhou, 215000, Jiangsu, China.
Guangxin Duan *Center for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Baoxing HuangCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Shanshan QiuCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Dandan ZhouCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Jianfeng ZengCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Jiabin CuiCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Chunhong HuDepartment of Radiology, The First Affiliated Hospital of Soochow University, Institute of Medical Imaging, Soochow University, 188 Shizi Street, Suzhou, 215000, Jiangsu, China.
Ximing WangDepartment of Radiology, The First Affiliated Hospital of Soochow University, Institute of Medical Imaging, Soochow University, 188 Shizi Street, Suzhou, 215000, Jiangsu, China. wangximing1998@163.com.
Ling WenDepartment of Radiology, The First Affiliated Hospital of Soochow University, Institute of Medical Imaging, Soochow University, 188 Shizi Street, Suzhou, 215000, Jiangsu, China. wenling@suda.edu.cn.ORCID http://orcid.org/0000-0003-1024-380X
Mingyuan GaoCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, 199 Renai Road, Suzhou, 215123, Jiangsu, China.

Funding

Young Scientists Fund 22006109Young Scientists Fund 81801751
6 · The paper itself

Abstract

backgroundFluorescence imaging as the beacon for optical navigation has wildly developed in preclinical studies due to its prominent advantages, including noninvasiveness and superior temporal resolution. However, the traditional optical methods based on ultraviolet (UV, 200-400 nm) and visible light (Vis, 400-650 nm) limited by their low penetration, signal-to-noise ratio, and high background auto-fluorescence interference. Therefore, the development of near-infrared-II (NIR-II 1000-1700 nm) nanoprobe attracted significant attentions toward in vivo imaging. Regrettably, most of the NIR-II fluorescence probes, especially for inorganic NPs, were hardly excreted from the reticuloendothelial system (RES), yielding the anonymous long-term circulatory safety issue.

resultsHere, we develop a facile strategy for the fabrication of Nd

conclusionsThe rationally designed Nd-RENPs nanoprobes manifest rapid-clearance property revealing the potential application toward the noninvasive preoperative imaging of tumor lesions and real-time intra-operative supervision.

Indexed as

Contrast MediaFluorescent DyesMetals, Rare EarthNanoparticlesAnimalsBreast NeoplasmsCell Line, TumorFemaleLiverMagnetic Resonance ImagingMiceMice, Inbred BALB COptical ImagingSpectroscopy, Near-InfraredContrast MediaFluorescent DyesMetals, Rare EarthDual-modal imagingNIR-II regionRapid liver clearanceRare-earth core–shell nanoparticles

Identifiers

PMID34789288
PMCPMC8600917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.