Evidence map›Paper›PMID 34789189›Full record

ArticleBMC ophthalmology2021

Frequently assessed and used prognostic factors for outcome after macular hole surgery: which is better?

M Roth, N Schön, L Jürgens, D Engineer, K Kirchhoff, R Guthoff, J Schmidt

Abstract read
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
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  7. Predicting Visual Recovery in Long-Standing Macular Holes: Surgical Strategies and Role of Optical Coherence Tomography Biomarkers.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  8. Article
  9. Prediction of long-term visual outcome of idiopathic full-thickness macular hole surgery using optical coherence tomography parameters that estimate potential preoperative photoreceptor damage.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  10. Article
  11. Choroidal hypertransmission width on optical coherence tomography: a prognostic biomarker in idiopathic macular hole surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M RothDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany. mathiasroth@gmx.net.
N SchönAugenklinik Tausendfensterhaus, Duisburg, Germany.
L JürgensDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
D EngineerAugenklinik Tausendfensterhaus, Duisburg, Germany.
K KirchhoffAugenklinik Tausendfensterhaus, Duisburg, Germany.
R GuthoffDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
J SchmidtAugenklinik Tausendfensterhaus, Duisburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this retrospective study was to evaluate commonly used clinical and OCT-morphological parameters, including perifoveal pseudocysts, as prognostic factors for postoperative outcome after macular hole surgery in a retinal referral clinic in North Rhine-Westphalia, Germany. METHODS AND MATERIAL: This was a retrospective analysis of all patients who underwent surgery because of idiopathic MH between 2011 and 2017 in Augenklinik Tausendfensterhaus, Duisburg, Germany. Statistical evaluation of clinical and OCT-based parameters, including the areas of intraretinal pseudocysts, was conducted. The main statistical outcomes were surgical success and visual acuity. Only parameters with a highly significant correlation to the outcome parameters (postoperative visual acuity (VA); surgical success) in univariate analysis were entered in linear and logistic regression analyses.

resultsA total of 189 eyes of 178 patients (71.4% female; mean age 67.5 ± 8.2 a) who underwent surgery because of MH were included. The overall closure rate was 86.8%. The mean best corrected VA increased from 0.7 ± 0.3 logMAR before surgery to 0.5 ± 0.3 logMAR (p < 0.0001). While several clinical and OCT-based parameters as well as calculated indices showed a significant correlation with the outcome measures, the regression analysis showed that the minimum linear diameter was the only parameter that both predicted surgical success (p = 0.015) and was correlated with postoperative VA (p < 0.001).

conclusionThe minimum linear diameter serves as an easily assessed prognostic factor with the best predictive properties. This result is of great importance for clinical practice, as it simplifies the postsurgical prognosis.

Indexed as

Retinal PerforationsAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVitrectomyMacular holeOptical coherence tomographyPrognostic parametersVitrectomyVitreoretinal surgery

Identifiers

PMID34789189
PMCPMC8600723

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.