ArticleBMC cardiovascular disorders2021
Usefulness of cardiac magnetic resonance images for prediction of sudden cardiac arrest in patients with mitral valve prolapse: a multicenter retrospective cohort study.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Arrhythmic risk in mitral valve prolapse with mitral annular disjunction: meta-analysis of longitudinal studies.Scientific reports · 2025Pooled it
- Role of cardiac magnetic resonance in stratifying arrhythmogenic risk in mitral valve prolapse patients: a systematic review and meta-analysis.European radiology · 2024Pooled it
- The Association Between Late Gadolinium Enhancement by Cardiac Magnetic Resonance and Ventricular Arrhythmia in Patients With Mitral Valve Prolapse: A Systematic Review and Meta-Analysis.Clinical cardiology · 2024Pooled it
- Mitral Valve Prolapse in Athletes: Prevalence, Arrhythmic Associations, and Clinical Implications-A Systematic Review.Journal of clinical medicine · 2025Review
- Mitral annular disjunction in out-of-hospital cardiac arrest patients-a retrospective cardiac MRI study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Arrhythmic Mitral Valve Prolapse: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2023Review
- Effects of Mitral Valve Prolapse on Quantification of Mitral Regurgitation and Ejection Fraction Using Cardiac MRI.Radiology. Cardiothoracic imaging · 2023Article
- The evolving role of cardiovascular magnetic resonance in the assessment of mitral valve prolapse.Frontiers in cardiovascular medicine · 2023Review
- A case report of arrhythmogenic mitral valve disease: still a long way to go.European heart journal. Case reports · 2022Article
- Developing a Mechanistic Approach to Sudden Death Prevention in Mitral Valve Prolapse.Journal of clinical medicine · 2022Review
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Authors and funding
22 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn association has been identified between mitral valve prolapse (MVP) and sudden cardiac arrest (SCA), and ventricular arrhythmias (VA). This study aimed to elucidate predictive factors for SCA or VA in MVP patients.
methodsMVP patients who underwent cardiac magnetic resonance (CMR) were retrospectively included. Patients with other structural heart disease or causes of aborted SCA were excluded. Clinical characteristics (sex, age, body mass index, histories of diabetes, hypertension, and dyslipidemia) and electrocardiographic (PR interval, QRS duration, corrected QT interval, inverted T wave in the inferior leads, bundle branch block, and atrial fibrillation), echocardiographic [mitral regurgitation grade, prolapsing mitral leaflet, and right ventricular systolic pressure (RVSP)], and CMR [left atrial volume index, both ventricular ejection fractions, both ventricular end-diastolic and systolic volume indexes, prolapse distance, mitral annular disjunction, systolic curling motion, presence of late gadolinium enhancement (LGE), LGE volume and proportion] parameters were analyzed.
resultsOf the 85 patients [age, 54.0 (41.0-65.0) years; 46 men], seven experienced SCA or VA. Younger age and wide QRS complex were observed more often in the SCA/VA group than in the no-SCA/VA group. The SCA/VA group exhibited lower RVSP, more systolic curling motion and LGE, greater LGE volume, and higher LGE proportion. The presence of LGE [hazard ratio (HR), 19.8; 95% confidence interval (CI) 2.65-148.15; P = 0.004], LGE volume (HR 1.08; 95% CI 1.02-1.14; P = 0.006) and LGE proportion (HR 1.32; 95% CI 1.08-1.60; P = 0.006) were independently associated with higher risk of SCA or VA in MVP patients together with systolic curling motion in each model.
conclusionsThe presence of systolic curling motion, high LGE volume and proportion, and the presence of LGE on CMR were independent predictive factors for SCA or VA in MVP patients.
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