Evidence map›Paper›PMID 34789044›Full record

ArticleInternational journal of immunopathology and pharmacology

The role of the sphingosine axis in immune regulation: A dichotomy in the anti-inflammatory effects between sphingosine kinase 1 and sphingosine kinase 2-dependent pathways.

Yuval Ishay, Dvorah Rotnemer-Golinkin, Yaron Ilan

Open access · goldAbstract read
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Opaganib Protects Against High-Fat Diet-Induced Hypercholesterolemia and Liver Steatosis in Mice.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuval IshayDepartment of Medicine, 58884Hadassah-Hebrew University Medical Center, Jerusalem Israel.
Dvorah Rotnemer-GolinkinDepartment of Medicine, 58884Hadassah-Hebrew University Medical Center, Jerusalem Israel.
Yaron IlanDepartment of Medicine, 58884Hadassah-Hebrew University Medical Center, Jerusalem Israel.ORCID https://orcid.org/0000-0003-0802-1220
Hadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Inflammatory AgentsHepatitis, AnimalInterferon-gammaLiverMaleMiceMice, Inbred C57BLPhosphotransferases (Alcohol Group Acceptor)Signal TransductionSphingosineSphingosine KinaseT-Lymphocyte SubsetsAnti-Inflammatory AgentsInterferon-gammaPhosphotransferases (Alcohol Group Acceptor)SphingosineSphingosine Kinaseimmune-mediated hepatitissphingolipidssphingosine kinase 1sphingosine kinase 2

Identifiers

PMID34789044
PMCPMC8645305
OpenAlexW3212416724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.