Evidence map›Paper›PMID 34788631›Full record

ArticleCell reports2021

COMMD10 is critical for Kupffer cell survival and controls Ly6C

Keren Cohen, Odelia Mouhadeb, Shani Ben Shlomo, Marva Langer, Anat Neumann, Noam Erez, Itay Moshkovits, Rotem Pelet, Daniel J Kedar, Eli Brazowski and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. COMMD10 inhibited DNA damage to promote the progression of gastric cancer.Journal of cancer research and clinical oncology · 2024
    Article
  6. Review
  7. Article
  8. Article
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  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Keren CohenResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel; Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Odelia MouhadebResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel; Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Shani Ben ShlomoResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.
Marva LangerResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel; Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Anat NeumannResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.
Noam ErezResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.
Itay MoshkovitsResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel; Internal Medicine T, Sourasky Medical Center, Tel-Aviv 64239, Israel.
Rotem PeletResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.
Daniel J KedarDepartment of Plastic and Reconstructive Surgery, Sourasky Medical Center, Tel-Aviv 64239, Israel.
Eli BrazowskiResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.
Martin GuilliamsVIB-UGent Center for Inflammation Research, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9052, Belgium.
Helen S GoodridgeBoard of Governors Regenerative Medicine Institute and Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Nathan GluckResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel. Electronic address: nathang@tlvmc.gov.il.
Chen VarolResearch Center for Digestive Tract and Liver Diseases, Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel; Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel. Electronic address: chenv@tlvmc.gov.il.
Tel Aviv University · ILCedars-Sinai Medical Center · USGhent University · BETel Aviv Sourasky Medical Center · IL

Funding

Monocyte Production by Bone Marrow ProgenitorsR01AI134987 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI GOODRIDGE, HELEN S · 2018 to 2022
$2.5M
NIAID NIH HHS R01 AI134987
6 · The paper itself

Abstract

Liver-resident macrophages Kupffer cells (KCs) and infiltrating Ly6C

Indexed as

AnimalsAntigens, LyCell DifferentiationCell SurvivalHematopoiesisInflammasomesInflammationIntracellular Signaling Peptides and ProteinsKupffer CellsLiverMaleMiceMice, Inbred C57BLMonocytesAntigens, LyCommd10 protein, mouseInflammasomesIntracellular Signaling Peptides and ProteinsLy-6C antigen, mouseCOMMD10dendritic cell like monocytesKupffer cellslarge peritoneal macrophageslipid-associated macrophagesLy6Chi monocytesneutrophil-like monocytes

Identifiers

PMID34788631
PMCPMC8998879
OpenAlexW3201988289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.