Evidence map›Paper›PMID 34788481›Full record

ArticleJournal of veterinary internal medicine2022

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States.

Erin Lashnits, Brendon Thatcher, Ariel Carruth, Anton Mestek, Jesse Buch, Melissa Beall, Pradeep Neupane, Ramaswamy Chandrashekar, Edward B Breitschwerdt

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Serological evidence of exposure to Bartonella sp. in dogs with suspected vector-borne diseases, toxoplasmosis and neosporosis.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erin LashnitsIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0003-0949-5698
Brendon ThatcherIDEXX Laboratories Inc., Westbrook, Maine, USA.
Ariel CarruthIDEXX Laboratories Inc., Westbrook, Maine, USA.
Anton MestekIDEXX Laboratories Inc., Westbrook, Maine, USA.
Jesse BuchIDEXX Laboratories Inc., Westbrook, Maine, USA.
Melissa BeallIDEXX Laboratories Inc., Westbrook, Maine, USA.
Pradeep NeupaneIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Ramaswamy ChandrashekarIDEXX Laboratories Inc., Westbrook, Maine, USA.
Edward B BreitschwerdtIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-5179-3720

Funding

Comparative Medicine and Translational Research Training ProgramT32OD011130 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Lauren Virginia Schnabel · 2012 to 2026
$7.8M
Comparative Medicine and Translational Medicine Research Program of the National Institutes of Health T32OD011130NIH HHS T32 OD011130
6 · The paper itself

Abstract

backgroundImproved understanding of Bartonella spp. serology in dogs may aid clinical decision making.

objectiveDescribe demographic and geographic patterns of Bartonella spp. seroreactivity in dogs, and describe hematologic and serum biochemical abnormalities in Bartonella spp. seroreactive and nonseroreactive dogs. ANIMALS: Serum samples from 5957 dogs in the United States, previously submitted to IDEXX Reference Laboratories.

methodsSerum was tested using 3 indirect ELISAs for B. henselae, B. vinsonii subsp. berkhoffii, and B. koehlerae. Complete blood count and serum biochemistry panel results were reviewed retrospectively.

resultsOverall, 6.1% of dogs were Bartonella spp. seroreactive. Toy breeds were less likely to be seroreactive (3.9%) than mixed breeds (7.5%; adjusted odds ratio [aOR], 0.48; 95% confidence interval [CI], 0.32-0.72), and dogs <1 year old were less likely to be seroreactive (3.4%) than dogs 1 to 5.5 years of age (7.3%; aOR, 0.42; 95% CI, 0.23-0.72). Dogs in the West South Central (9.8%) and South Atlantic (8.8%) regions were more likely than dogs elsewhere in the United States to be seroreactive (aOR, 2.22; 95% CI, 1.31-3.87; aOR, 2.44; 95% CI, 1.38-4.36). CONCLUSIONS AND CLINICAL IMPORTANCE: Demographic and geographic findings for Bartonella spp. exposure were broadly comparable to previously reported patterns.

Indexed as

BartonellaBartonella InfectionsDog DiseasesAnimalsDogsRetrospective StudiesSeroepidemiologic StudiesUnited Statesbartonellosiscanineseroreactivityvector-bornezoonoses

Identifiers

PMID34788481
PMCPMC8783365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.