Evidence map›Paper›PMID 34788281›Full record

ArticlePLoS neglected tropical diseases2021

Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.

Carla Bellomo, Daniel Oscar Alonso, Tamara Ricardo, Rocío Coelho, Sebastián Kehl, Natalia Periolo, Viviana Azogaray, Natalia Casas, Mariano Ottonelli, Laura Cristina Bergero and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  8. Mathematical Model of the Spread of Hantavirus Infection.Pathogens (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Carla BellomoInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.ORCID 0000-0001-6869-1707
Daniel Oscar AlonsoInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.ORCID 0000-0003-3605-4679
Tamara RicardoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fé, Argentina.ORCID 0000-0002-0921-2611
Rocío CoelhoInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.ORCID 0000-0002-7274-9315
Sebastián KehlInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.
Natalia PerioloInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.ORCID 0000-0002-2077-720X
Viviana AzogarayLaboratorio Central de la Provincia de Santa Fe, Santa Fé, Argentina.
Natalia CasasMinisterio de Salud de la Nación, Programa Nacional de Control de Enfermedades Zoonóticas, Buenos Aires, Argentina.
Mariano OttonelliDirección de Epidemiología, Ministerio de Salud de Santa Fe, Santa Fé, Argentina.ORCID 0000-0003-1649-8336
Laura Cristina BergeroConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fé, Argentina.ORCID 0000-0002-3387-6274
María Carolina CudósDirección de Epidemiología, Ministerio de Salud de Santa Fe, Santa Fé, Argentina.ORCID 0000-0003-1950-5001
María Andrea PrevitaliConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fé, Argentina.
Valeria Paula MartinezInstituto Nacional de Enfermedades Infecciosas-Administración Nacional de Laboratorios e Institutos de Salud "Dr. C. Malbrán", Buenos Aires, Argentina.ORCID 0000-0002-4356-8136
Administración Nacional de Laboratorios e Institutos de Salud · ARMinisterio de Salud · ARCentro Científico Tecnológico - Santa Fe · ARUniversidad Nacional del Litoral · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthohantaviruses are emerging rodent-borne pathogens that cause Hantavirus Pulmonary Syndrome in humans. They have a wide range of rodent reservoir hosts and are transmitted to humans through aerosolized viral particles generated by the excretions of infected individuals. Since the first description of HPS in Argentina, new hantaviruses have been reported throughout the country, most of which are pathogenic to humans. We present here the first HPS case infected with Alto Paraguay virus reported in Argentina. Until now, Alto Paraguay virus was considered a non-pathogenic orthohantavirus since it was identified in a rodent, Holochilus chacarius. In addition to this, with the goal of identifying potential hantavirus host species in the province of Santa Fe, we finally describe a novel orthohantavirus found in the native rodent Scapteromys aquaticus, which differed from other hantaviruses described in the country so far. Our findings implicate an epidemiological warning regarding these new orthohantaviruses circulating in Central Argentina as well as new rodent species that must be considered as hosts from now on.

Indexed as

AdolescentAnimalsAntibodies, ViralArgentinaDisease ReservoirsFemaleHantavirus Pulmonary SyndromeHumansMaleOrthohantavirusPhylogenySigmodontinaeAntibodies, Viral

Identifiers

PMID34788281
PMCPMC8598061
OpenAlexW3213310557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.