Evidence map›Paper›PMID 34788129›Full record

ArticleMolecular biology of the cell2022

A chemorepellent inhibits local Ras activation to inhibit pseudopod formation to bias cell movement away from the chemorepellent.

Sara A Kirolos, Richard H Gomer

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Two endogenousProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Identification of novel proteins in themicroPublication biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sara A KirolosDepartment of Biology, Texas A&M University, College Station, TX 77843-3474.
Richard H GomerDepartment of Biology, Texas A&M University, College Station, TX 77843-3474.
Texas A&M University · US

Funding

Elucidation of a Eukaryotic Chemorepulsion MechanismR35GM139486 · NIGMS · TEXAS A&M UNIVERSITY · PI Richard H Gomer · 2021 to 2026
$2.3M
Elucidation of a eukaryotic chemorepulsion mechanismR01GM118355 · NIGMS · TEXAS A&M UNIVERSITY · PI GOMER, RICHARD H · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM118355NIGMS NIH HHS R35 GM139486
6 · The paper itself

Abstract

The ability of cells to sense chemical gradients is essential during development, morphogenesis, and immune responses. Although much is known about chemoattraction, chemorepulsion remains poorly understood. Proliferating

Indexed as

Cell Migration InhibitionCell MovementCell ProliferationChemotaxisDictyosteliumExtracellular Signal-Regulated MAP Kinasesp21-Activated KinasesProtozoan ProteinsPseudopodiaras ProteinsReceptors, G-Protein-CoupledSignal TransductionExtracellular Signal-Regulated MAP Kinasesp21-Activated KinasesProtozoan Proteinsras ProteinsReceptors, G-Protein-Coupled

Identifiers

PMID34788129
PMCPMC8886819
OpenAlexW3211921446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.