Evidence map›Paper›PMID 34788016›Full record

ArticleEnvironmental science & technology2021

Marine and Anthropogenic Bromopyrroles Alter Cellular Ca

Jing Zheng, Shane Antrobus, Wei Feng, Trevor N Purdy, Bradley S Moore, Isaac N Pessah

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jing ZhengDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California 95616, United States.
Shane AntrobusDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California 95616, United States.
Wei FengDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California 95616, United States.
Trevor N PurdyCenter for Marine Biotechnology and Biomedicine, University of California, San Diego, California 92037, United States.
Bradley S MooreCenter for Marine Biotechnology and Biomedicine, University of California, San Diego, California 92037, United States.ORCID 0000-0002-4652-1253
Isaac N PessahDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California 95616, United States.ORCID 0000-0002-8149-588X
University of California, Davis · USScripps Institution of Oceanography · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Molecular Mechanisms of Marine Organohalogen Bioaccumulation and NeurotoxicityR01ES030318 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMDOUN, AMRO M, PESSAH, ISAAC N · 2018 to 2022
$826k
Natural Sources and Microbial Transformation of Marine Halogenated PollutantsR01ES030316 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALLEN, ERIC ELLSWORTH, MOORE, BRADLEY S · 2018 to 2022
$669k
NCI NIH HHS P30 CA093373NIEHS NIH HHS R01 ES030316NIEHS NIH HHS R01 ES030318
6 · The paper itself

Abstract

Bromopyrroles (BrPyr) are synthesized naturally by marine sponge symbionts and produced anthropogenically as byproducts of wastewater treatment. BrPyr interact with ryanodine receptors (RYRs) and sarco/endoplasmic reticulum (SR/ER) Ca

Indexed as

Adenosine TriphosphatasesRyanodine Receptor Calcium Release ChannelAnimalsCalciumEndoplasmic ReticulumHEK293 CellsHumansMiceAdenosine TriphosphatasesCalciumRyanodine Receptor Calcium Release ChannelbromopyrrolesCa2+ homeostasisdisinfectant byproductsmarine organohalogensneurotoxicityryanodine receptorssarco/endoplasmic reticulum Ca2+-ATPase (SERCA)structure−activity relationship

Identifiers

PMID34788016
PMCPMC8813095
OpenAlexW3212339710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.