Evidence map›Paper›PMID 34787891›Full record

ArticleCardiology journal

IMPACT of PCSK9 inhibition on clinical outcome in patients during the inflammatory stage of the SARS-COV-2 infection: Rationale and protocol of the IMPACT-SIRIO 5 study.

Jacek Kubica, Przemysław Podhajski, Przemysław Magielski, Aldona Kubica, Piotr Adamski, Roman Junik, Jarosław Pinkas, Eliano P Navarese

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. PCSK9 Inhibition During the Inflammatory Stage of SARS-CoV-2 Infection.Journal of the American College of Cardiology · 2023
    Trial
  2. PCSK9 in critical illness - It's not all about lipids.Annals of clinical biochemistry · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jacek KubicaDepartment of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Poland.
Przemysław PodhajskiDepartment of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Poland. przemo.podhajski@gmail.com.
Przemysław MagielskiDepartment of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Poland.
Aldona KubicaDepartment of Health Promotion, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Poland.
Piotr AdamskiDepartment of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Poland.
Roman JunikDepartment of Endocrinology and Diabetology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Jarosław PinkasCentre of Postgraduate Medical Education, School of Public Health, Warsaw, Poland.
Eliano P NavareseDepartment of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Poland.
Nicolaus Copernicus University · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Proprotein Convertase 9CarbidopaDrug CombinationsHumansLevodopaSARS-CoV-2CarbidopaDrug CombinationsLevodopaPCSK9 protein, humanProprotein Convertase 9sirio

Identifiers

PMID34787891
PMCPMC8890419
OpenAlexW3213758588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.