Evidence map›Paper›PMID 34787796›Full record

ArticleJournal of nephrology2022

Low performance of prognostic tools for predicting death before dialysis in older patients with advanced CKD.

Julien Prouvot, Emilie Pambrun, Valery Antoine, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Maud Francois, Christophe Mariat, Daniela Babici, Camelia Prelipcean and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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  9. Physical Function and Mortality in Older Adults with Chronic Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Julien ProuvotIDESP, INSERM Université de Montpellier, Montpellier, France.ORCID 0000-0001-5944-5598
Emilie PambrunService Néphrologie-Dialyses-Aphérèses, Hôpital Universitaire de Nîmes, CHU Caremeau, Place du Pr Debré, 30000, Nimes, France.
Valery AntoineIDESP, INSERM Université de Montpellier, Montpellier, France.
Cecile CouchoudRegistre REIN, Agence de la Biomedecine, Saint-Denis La Plaine, France.
Cecile VigneauCHU Pontchaillou, Service de Néphrologie-Dialyse-Transplantation, Université Rennes 1, IRSET, Rennes, France.
Sophie RocheService de Nephrologie‑Dialyse, CH Macon, Macon, France.
Maud FrancoisService de Néphrologie-Dialyse-Transplantation, CHU Tours, Tours, France.
Christophe MariatService de Néphrologie, Hôpital Nord, Centre Hospitalier Universitaire de Saint-Étienne, 42055, Saint-Étienne Cedex 02, France.
Daniela BabiciService Néphrologie-Dialyse, GHR MSA, Hôpital Emile Muller, Mulhouse, France.
Camelia PrelipceanService Néphrologie-Dialyses-Aphérèses, Hôpital Universitaire de Nîmes, CHU Caremeau, Place du Pr Debré, 30000, Nimes, France.
Olivier MoranneIDESP, INSERM Université de Montpellier, Montpellier, France. olivier.moranne@chu-nimes.fr.ORCID 0000-0002-3127-1415
PSPA Investigators
Centre Hospitalier Universitaire de Nîmes · FRInserm · FRCentre Hospitalier Compiègne-Noyon · FRCentre Hospitalier Universitaire de Saint-Étienne · FRCentre Hospitalier Universitaire de Tours · FRCentre National de la Recherche Scientifique · FRHôpital Émile-Roux · FRInstitut de Recherche en Santé, Environnement et Travail · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) is a disease which is spreading worldwide, especially among older patients. Several prognostic scores have been developed to predict death in older CKD patients, but they have not been validated. We aimed to evaluate the existing risk scores for predicting death before dialysis start, identified via an in-depth review, in a cohort of elderly patients with advanced CKD.

methodsWe performed a review to identify scores predicting death, developed in and applicable to CKD patients. Each score was evaluated with an absolute risk calculation from the patients' baseline characteristics. We used a French prospective multicentre cohort of elderly patients (> 75 years) with advanced CKD [estimated glomerular filtration rate (eGFR) < 20 mL/min/1.73 m

resultsOur review found 6 equations predicting death before dialysis in CKD patients. Four of these (GOLDFARB, BANSAL, GRAMS 2 and 4 years) were evaluated. The validation cohort (Parcours de Soins des Personnes Âgées Parcours de Soins des Personnes Âgées, PSPA) included 573 patients, with a median age of 82 years and a median eGFR of 13 mL/min/1.73 m DISCUSSION: The available scores predicting death before dialysis showed low performance among older patients with advanced CKD in a French multicentre cohort, indicating the need to upgrade them or develop new scores for this population.

Indexed as

Renal DialysisRenal Insufficiency, ChronicAgedAged, 80 and overDisease ProgressionGlomerular Filtration RateHumansPrognosisProspective StudiesRisk FactorsCKDElderlyESRDPrognosis

Identifiers

PMID34787796
OpenAlexW3211597030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.