Evidence map›Paper›PMID 34787473›Full record

ArticleInnate immunity2021

Circulating

Vuyolwethu Mxinwa, Phiwayinkosi V Dludla, Tawanda M Nyambuya, Bongani B Nkambule

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Vuyolwethu MxinwaSchool of Laboratory Medicine and Medical Sciences (SLMMS), College of Health Sciences, 56394University of KwaZulu-Natal, Durban, South Africa.
Phiwayinkosi V DludlaBiomedical Research and Innovation Platform, 59097South African Medical Research Council, Tygerberg, South Africa.
Tawanda M NyambuyaSchool of Laboratory Medicine and Medical Sciences (SLMMS), College of Health Sciences, 56394University of KwaZulu-Natal, Durban, South Africa.
Bongani B NkambuleSchool of Laboratory Medicine and Medical Sciences (SLMMS), College of Health Sciences, 56394University of KwaZulu-Natal, Durban, South Africa.ORCID 0000-0001-8846-1992
University of KwaZulu-Natal · ZANamibia University of Science and Technology · NASouth African Medical Research Council · ZA

Funding

Developing Research Innovation, Localization and Leadership in South Africa (DRILL)D43TW010131 · FIC · UNIVERSITY OF KWAZULU-NATAL · PI BRYSIEWICZ, PETRA, MOSHABELA, MOSA · 2015 to 2019
$3.2M
FIC NIH HHS D43 TW010131
6 · The paper itself

Abstract

Impaired Glc tolerance and hyperinsulinemia are a hallmark of type 2 diabetes (T2D) and are associated with an altered innate and adaptive immune response. In this study, we used a high-fat diet (HFD)-induced model of pre-diabetes to explore the pathological implications of altered innate lymphoid cell (ILC) profiles in a state of impaired Glc tolerance. Sixteen male C57BL/6 mice were randomized to receive two experimental diets (

Indexed as

Diabetes Mellitus, Type 2Diet, High-FatAnimalsCytokinesImmunity, InnateLymphocytesMaleMiceMice, Inbred C57BLCytokinesGlc metabolisminflammationinnate lymphoid cellsinsulin resistancetype 2 diabetes mellitus

Identifiers

PMID34787473
PMCPMC8762092
OpenAlexW3212643377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.