Evidence map›Paper›PMID 34787338›Full record

ArticleAndrologia2022

Rapid cryopreservation of small quantities of human spermatozoa by a self-prepared cryoprotectant without animal component.

Shasha Liu, Bo Liu, Wenrui Zhao, Xiao Liu, Yang Xian, Qingyuan Cheng, Min Jiang, Huanxun Yue, Fuping Li

Open access · hybridAbstract read
In one paragraph

Article in Andrologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shasha LiuHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Bo LiuHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Wenrui ZhaoHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Xiao LiuHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Yang XianHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Qingyuan ChengHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Min JiangHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Huanxun YueHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.
Fuping LiHuman Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-5183-4214
Ministry of Education of the People's Republic of China · CN

Funding

National Natural Science Foundation of China 81974226
6 · The paper itself

Abstract

Cryopreservation of small quantities of human spermatozoa whilst maintaining adequate post-thawing motility has been found an essential challenge for male fertility preservation. Therefore, the study used an effective, and convenient rapid-freezing method to freeze small amounts of human spermatozoa by adding self-prepared cryoprotectant (SPC) without animal component. In the feasibility experiment, no significant differences in progressive motility, normal sperm morphology, vitality or DNA fragmentation index between the conventional slow freezing and rapid freezing were realised. The present study prospectively analysed the effects of sperm freezing and resuscitation in 175 patients with severe oligozoospermia (sperm concentration <1 × 10

Indexed as

Semen PreservationAnimalsCryopreservationCryoprotective AgentsFreezingHumansMaleSpermatozoaSperm MotilityCryoprotective Agentsconventional slow freezingrapid freezingself-prepared cryoprotectantsmall quantities of human spermatozoa

Identifiers

PMID34787338
PMCPMC9285689
OpenAlexW3212888749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.