Evidence map›Paper›PMID 34787058›Full record

ArticleBioengineered2022

CircSLC7A6 promotes the progression of Wilms' tumor via microRNA-107/ ABL proto-oncogene 2 axis.

Jiaju Xu, Ying Hao, Xingjuan Gao, Yanqiu Wu, Yanjie Ding, Baohong Wang

RetractedAbstract readRetracted Publication
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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  4. Article
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  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jiaju XuDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.
Ying HaoDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.
Xingjuan GaoDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.
Yanqiu WuDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.
Yanjie DingDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.
Baohong WangDepartment of Pediatrics, Yantai Yuhuangding Hospital, Yantai City, China.ORCID 0000-0003-0662-4511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dysregulation of circular RNAs (circRNAs) has been proved to be involved in the carcinogenesis of various cancers. Nevertheless, the biological function of circSLC7A6 remains unclear in Wilms' tumor (WT). In our study, we found that circSLC7A6 was upregulated in cancerous WT tissues and cells. Cell apoptosis was increased while cell viability, migration, and invasion were repressed by circSLC7A6 silencing. Besides, circSLC7A6 knockdown suppressed WT tumor growth

Indexed as

Up-RegulationAnimalsApoptosisBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHumansMiceMicroRNAsNeoplasm TransplantationProtein-Tyrosine KinasesRNA, CircularWilms TumorARG tyrosine kinaseBiomarkers, TumorMicroRNAsMIRN107 microRNA, humanProtein-Tyrosine KinasesRNA, CircularABL2CIRCSLC7A6miR-107Wilms’ tumor

Identifiers

PMID34787058
PMCPMC8805947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.