Evidence map›Paper›PMID 34787019›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Expressing

Yuling Huang, Liu Feng, Yongqiang Bao, Yun Zhang, Jinghui Liang, Qingfeng Mao, Jingao Li, Chunling Jiang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuling HuangDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Liu FengDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Yongqiang BaoDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Yun ZhangDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Jinghui LiangDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Qingfeng MaoDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Jingao LiDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.
Chunling JiangDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi 330029, China.ORCID 0000-0002-1214-5325
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mut L homolog-1 (MLH1) is a key DNA mismatch repair protein which participates in the sensitivity to DNA damaging agents. However, its role in the radiosensitivity of tumor cells is less well characterized. In this study, we investigated the role of MLH1 in cellular responses to ionizing radiation (IR) and explored the signaling molecules involved. The isogenic pair of MLH1 proficient (MLH1

Indexed as

Antineoplastic AgentsCyclic AMP-Dependent Protein Kinase Catalytic SubunitsMutL Protein Homolog 1Radiation ToleranceHCT116 CellsHistonesHumansAntineoplastic AgentsCyclic AMP-Dependent Protein Kinase Catalytic SubunitsH2AX protein, humanHistonesMLH1 protein, humanMutL Protein Homolog 1PRKACA protein, humanHCT116 cellsionizing radiationMut L homolog-1protein kinase A catalytic subunitradiosensitivity

Identifiers

PMID34787019
PMCPMC8919320
OpenAlexW3212605884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.