Evidence map›Paper›PMID 34787015›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2022

A novel intracranial exchange guidewire improves the navigation of various endovascular devices: An in vitro study of challenging situations.

Naoki Kaneko, Ariel Takayanagi, Hamidreza Saber, Lea Guo, Satoshi Tateshima

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. First-in-human trial of Center Wire for neuroendovascular therapy to avoid guidewire-related complications.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Trial
  2. Article
  3. Bailout Guiding Catheter Exchange Using Medilizer: A Case Report.Journal of neuroendovascular therapy · 2026
    Article
  4. Microguidewire stiffness for microcatheter and aspiration catheter navigation in tortuous vessels.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Naoki KanekoDepartment of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-3579-7908
Ariel TakayanagiDepartment of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-4358-2528
Hamidreza SaberDepartment of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA.
Lea GuoDepartment of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA.
Satoshi TateshimaDepartment of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNeuroendovascular procedures rely on successful navigation and stable access to the target vessel. The Stabilizer is a 300 cm long exchange wire with a 0.014 diameter and a soft, flexible stent at the distal end designed to assist with navigation and device delivery. This study aims to assess the efficacy of the Stabilizer for navigation in a variety of challenging environments.

methodsThe efficacy of the Stabilizer was evaluated using three challenging vascular models: a giant aneurysm model, a severe tortuosity model, and an M1 stenosis model. The Stabilizer was compared with a conventional wire during navigation in each model.

resultsIn the giant aneurysm model, there was no significant difference of success during straightening of a looped wire and significantly higher success rates when advancing an intermediate catheter with the Stabilizer beyond the aneurysm neck compared to a conventional guidewire. The Stabilizer also significantly increased success rates when advancing an intermediate catheter through a model with severe tortuosity compared to a conventional guidewire, as well as exchange maneuver for intracranial stenting in a stenosis model compared to an exchange wire.

conclusionsIn our experimental model, the Stabilizer significantly improved navigation and device delivery in a variety of challenging settings compared to conventional wires.

Indexed as

Endovascular ProceduresStentsAneurysmCatheterizationCathetersConstriction, PathologicHumansanchoring techniqueexchange wiregiant aneurysmNavigationtortuosity

Identifiers

PMID34787015
PMCPMC9511615
OpenAlexW3213470301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.