Evidence map›Paper›PMID 34786874›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges.

Claire Bomkamp, Stacey C Skaalure, Gonçalo F Fernando, Tom Ben-Arye, Elliot W Swartz, Elizabeth A Specht

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion.Journal of biomedical materials research. Part A · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Assessment of Bovine Collagen Manufactured via Cellular Agriculture.ACS biomaterials science & engineering · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claire BomkampThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.ORCID 0000-0002-7259-5248
Stacey C SkaalureThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.ORCID 0000-0001-5746-0575
Gonçalo F FernandoThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.
Tom Ben-AryeThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.ORCID 0000-0001-9859-0931
Elliot W SwartzThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.ORCID 0000-0003-1779-5631
Elizabeth A SpechtThe Good Food Institute, 1380 Monroe St. NW #229, Washington, DC, 20010, USA.ORCID 0000-0002-2876-7452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cultivating meat from stem cells rather than by raising animals is a promising solution to concerns about the negative externalities of meat production. For cultivated meat to fully mimic conventional meat's organoleptic and nutritional properties, innovations in scaffolding technology are required. Many scaffolding technologies are already developed for use in biomedical tissue engineering. However, cultivated meat production comes with a unique set of constraints related to the scale and cost of production as well as the necessary attributes of the final product, such as texture and food safety. This review discusses the properties of vertebrate skeletal muscle that will need to be replicated in a successful product and the current state of scaffolding innovation within the cultivated meat industry, highlighting promising scaffold materials and techniques that can be applied to cultivated meat development. Recommendations are provided for future research into scaffolds capable of supporting the growth of high-quality meat while minimizing production costs. Although the development of appropriate scaffolds for cultivated meat is challenging, it is also tractable and provides novel opportunities to customize meat properties.

Indexed as

MeatTissue ScaffoldsBiocompatible MaterialsMuscle, SkeletalStem CellsTissue EngineeringBiocompatible Materialsbiomaterialsbioprintingcell-based meatcultivated meatcultured meatscaffoldingtissue engineering

Identifiers

PMID34786874
PMCPMC8787436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.