Evidence map›Paper›PMID 34786833›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022

ARMADA: Assessing reliable measurement in Alzheimer's disease and cognitive aging project methods.

Sandra Weintraub, Tatiana Karpouzian-Rogers, John Devin Peipert, Cindy Nowinski, Jerry Slotkin, Katy Wortman, Emily Ho, Emily Rogalski, Cynthia Carlsson, Bruno Giordani and 11 more

Abstract readMulticenter Study
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  8. Measuring Multidimensional Aspects of Health in the Oldest Old Using the NIH Toolbox: Results From the ARMADA Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  9. Exploring symptom clusters in mild cognitive impairment and dementia with the NIH Toolbox.Journal of the International Neuropsychological Society : JINS · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. The structural and social determinants of Alzheimer's disease related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  14. Baseline characterization of the ARMADA (Assessing Reliable Measurement in Alzheimer's Disease) study cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  15. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Sandra WeintraubMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Tatiana Karpouzian-RogersMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
John Devin PeipertDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Cindy NowinskiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Jerry SlotkinCenter for Health Assessment Research and Translation, University of Delaware, Newark, Delaware, USA.
Katy WortmanDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Emily HoDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Emily RogalskiMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Cynthia CarlssonDepartment of Medicine, University of Wisconsin-Madison School of Medicine and Public Health and Wisconsin Alzheimer's Disease Research Center, Madison, Wisconsin, USA.
Bruno GiordaniDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.
Felicia GoldsteinDepartment of Neurology, Emory University, Atlanta, Georgia, USA.
John LucasDepartment of Psychiatry and Psychology, Mayo Clinic, Jacksonville, Florida, USA.
Jennifer J ManlyDepartment of Neurology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, Columbia University, New York, New York, USA.
Dorene RentzDepartment of Neurology, Massachusetts General Hospital and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
David SalmonDepartment of Neurosciences, University of California San Diego, La Jolla, California, USA.
Beth SnitzDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hiroko H DodgeDepartment of Neurology, Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland, Oregon, USA.
Michaela RileyMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Fatima EldesMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Vitali UstsinovichDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Richard GershonDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
NATIONAL ALZHEIMERS COORDINATING CENTER (NACC)U01AG016976 · NIA · UNIVERSITY OF WASHINGTON · PI KUKULL, WALTER ANTHONY · 1999 to 2020
$72.8M
Vascular Moderators of the Impact of Alzheimer's Pathology in the Young-OldP01AG025204 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ann D. Cohen · 2005 to 2026
$56.5M
Vascular factors, physical activity, and inflammation as modulators of neurodegenerative and cognitive trajectories (Project 2)P01AG036694 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Rachel Frances Buckley, Keith A. Johnson · 2010 to 2026
$50.2M
National Alzheimer's Coordinating CenterU24AG072122 · NIA · UNIVERSITY OF WASHINGTON · PI STEPHENS, KARI A · 2021 to 2025
$45.8M
TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKER, JAMES T. · 1985 to 2019
$43.0M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI VEMURI, PRASHANTHI · 1999 to 2018
$36.9M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI MATTHEW P FROSCH · 2019 to 2026
$36.5M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2019 to 2026
$34.9M
Wisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sanjay Asthana · 2019 to 2026
$34.5M
Research Education ComponentP30AG066468 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI C. Elizabeth Shaaban · 2020 to 2026
$29.4M
The Goizueta Alzheimer's Disease Research CenterP30AG066511 · NIA · EMORY UNIVERSITY · PI Jonathan David Glass · 2020 to 2026
$29.0M
NCATS NIH HHS UL1 TR001873NIA NIH HHS P01 AG007232NIA NIH HHS P01 AG025204NIA NIH HHS P01 AG036694NIA NIH HHS P30 AG013854NIA NIH HHS P30 AG053760NIA NIH HHS P30 AG062421NIA NIH HHS P30 AG062429NIA NIH HHS P30 AG062715NIA NIH HHS P30 AG066468NIA NIH HHS P30 AG066511NIA NIH HHS P30 AG066518NIA NIH HHS P30 AG072977NIA NIH HHS P50 AG005133NIA NIH HHS P50 AG016574NIA NIH HHS P50 AG033514NIA NIH HHS R01 AG037212NIA NIH HHS R01 AG045571NIA NIH HHS R01 AG052446NIA NIH HHS R01 AG054484NIA NIH HHS R01 AG058724NIA NIH HHS R01 AG067781NIA NIH HHS R56 AG045571NIA NIH HHS RF1 AG047866NIA NIH HHS RF1 AG054023NIA NIH HHS U01 AG016976NIA NIH HHS U19 AG073153NIA NIH HHS U24 AG072122NIA NIH HHS U2C AG057441
6 · The paper itself

Abstract

introductionEarly detection of cognitive decline in older adults is a public health priority. Advancing Reliable Measurement in Alzheimer's Disease and Cognitive Aging (ARMADA), a multisite study, is validating cognition, emotion, motor, and sensory modules of the National Institutes of Health Toolbox for Assessment of Neurological and Behavioral Function (NIHTB) in the aging spectrum from cognitively normal to dementia of the Alzheimer's type (DAT).

methodsParticipants 65 to 85 years old, in demographic groups racially proportional to the general US population, are recruited in one of three groups to validate the NIHTB: cognitively normal, amnestic mild cognitive impairment (aMCI), or mild DAT. Additional special emphasis cohorts include (1) Blacks in the three clinical groups; (2) Spanish-speakers in the three clinical groups; (3) cognitively normal, population-proportional, over age 85. DISCUSSION: Longitudinal study will determine whether NIHTB can predict cognitive decline and is associated with Alzheimer's disease biomarkers. Here, we detail the methods for the ARMADA study.

Indexed as

Alzheimer DiseaseCognitive AgingCognitive DysfunctionAgedAged, 80 and overAgingHumansLongitudinal StudiesNeuropsychological TestsAlzheimer's diseasecognitiondementiamild cognitive impairmentneuropsychologyNIH Toolbox

Identifiers

PMID34786833
PMCPMC9110564

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.