Evidence map›Paper›PMID 34786824›Full record

ArticlePediatric blood & cancer2022

SARS-CoV-2 vaccine acceptability among caregivers of childhood cancer survivors.

Courtney E Wimberly, Lisa Towry, Elizabeth Davis, Emily E Johnston, Kyle M Walsh

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Courtney E WimberlyDivision of Neuro-Epidemiology, Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-7396-3479
Lisa TowryAlex's Lemonade Stand Foundation, Bala Cynwyd, Pennsylvania, USA.
Elizabeth DavisInstitute for Cancer Survivorship and Outcomes, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Emily E JohnstonInstitute for Cancer Survivorship and Outcomes, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0001-9126-2169
Kyle M WalshDivision of Neuro-Epidemiology, Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-5879-9981
Duke University · USUniversity of Alabama at Birmingham · USAlex's Lemonade Stand Foundation · US

Funding

Immune Correlates and Mechanisms of Perinatal Cytomegalovirus Infection and Later Life ALL DevelopmentR21CA242439 · NCI · DUKE UNIVERSITY · PI WALSH, KYLE M · 2019 to 2020
$385k
NCI NIH HHS R21 CA242439
6 · The paper itself

Abstract

objectiveTo explore willingness/hesitancy to vaccinate self and children against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among caregivers of childhood cancer survivors (CCS).

methodsA 19-question survey was sent to caregivers of CCS and completed between February 25 and April 13, 2021. Logistic regression was used to investigate relationships between willingness/hesitancy to vaccinate (a) self and (b) CCS, and demographic variables, confidence in the government and medical community's responses to coronavirus disease 2019 (COVID-19), and factors specific to the CCS community (e.g., previous participation in an investigational therapeutic trial).

resultsCaregivers (6% male) from 130 unique families completed the survey. Mean CCS age at survey was 15 years (SD 6.4). Mean CCS age at diagnosis was 4.3 years (SD 4.3). Mean time from CCS diagnosis to survey completion was 10 years (SD 6.2). Twenty-one percent of caregivers expressed hesitancy to vaccinate themselves and 29% expressed hesitancy to vaccinate their CCS. Caregivers expressing confidence in the federal government's response to COVID-19 were six-fold likelier to express willingness to self-vaccinate (p < .001) and were three-fold likelier to express willingness to vaccinate their CCS (p = .011). Qualitative analysis of free-text responses revealed three general themes, including (a) confidence in science, medicine, and vaccination as a strategy for health promotion, (b) confidence in SARS-CoV-2 vaccination and belief that CCS are at greater risk of COVID-19 complications, and (c) concerns about the swiftness of COVID-19 vaccine development and insufficient safety/efficacy data in children and CCS.

conclusionsResults underscore the need for COVID-19 vaccination education and outreach, even among families highly engaged with the medical community, and emphasize the importance of updating these families as relevant data emerge from vaccine trials and registries.

Indexed as

Cancer SurvivorsCOVID-19NeoplasmsCaregiversChildCOVID-19 VaccinesCross-Sectional StudiesFemaleHumansMaleSARS-CoV-2VaccinationCOVID-19 Vaccineschildhood cancerCOVID-19SARS-CoV-2vaccine acceptabilityvaccine hesitancy

Identifiers

PMID34786824
PMCPMC8661918
OpenAlexW3214312867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.