ArticlePlant biotechnology journal2022
Transcriptional activation of rice CINNAMOYL-CoA REDUCTASE 10 by OsNAC5, contributes to drought tolerance by modulating lignin accumulation in roots.
Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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54 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.
- A systematic review of single-cell RNA sequencing applications and insights in Oryza sativa response to environmental stresses.Molecular biology reports · 2025Pooled it
- Mulberry ERF Transcription Factor MnERF23 Is a Positive Regulator of Plant Drought Tolerance.Plants (Basel, Switzerland) · 2026Article
- Knocking out a wall-associated kinase gene enhances rice resistance to planthoppers in the field.Pest management science · 2026Article
- Nostoc sp. extract enhances rice lodging resistance by remodeling the gene expression network: mechanism and field application.BMC plant biology · 2026Article
- The genome of Cynanchum thesioides (Freyn) K. Schum provides insights into its systematics and candidate genes potentially associated with drought tolerance as a xerophyte.BMC plant biology · 2026Article
- Genome-Wide Characterization and Expression Profiling of theLife (Basel, Switzerland) · 2026Article
- Integrated Transcriptomic and Metabolic Analyses Reveal Key Defense Pathways AgainstPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Analysis of the Cinnamoyl-CoA Reductase (CCR) Gene Family and Its Involvement in Lignin Biosynthesis and Stress Responses in Six Tea Plant Cultivars.International journal of molecular sciences · 2026Article
- Bi-functional transcription factor FnZHD9 regulates leaf curling and drought resistance in fragaria nilgerrensis.BMC plant biology · 2026Article
- Regulatory Roles of MYB Transcription Factors in Root Barrier Under Abiotic Stress.Plants (Basel, Switzerland) · 2026Review
- MsCCoAOMTh3 confers drought tolerance by mediating lignin content and ROS scavenging.Plant molecular biology · 2026Article
- Integrative physiological and transcriptome analysis ofFrontiers in plant science · 2026Article
- SQUAMOSA-Promoter Binding Protein Like 10/14 (OsSPL10/14) Regulate Salt Tolerance by Modulating Reactive Oxygen Species Homeostasis in Rice (Oryza Sativa L.).Rice (New York, N.Y.) · 2025Article
- Rice Cinnamoyl CoA Reductase-like GenePlants (Basel, Switzerland) · 2025Article
- Chromosome-level genome assembly of Albizia odoratissima and effect of flavonoid metabolic pathways under drought stress.BMC plant biology · 2025Article
- Article
- Integrated transcriptome-metabolome analysis reveals oleanolic acid as a central regulator of heat stress adaptation in Rhododendron moulmainense.BMC plant biology · 2025Article
- Lignin Biosynthesis Driven byPlants (Basel, Switzerland) · 2025Article
- Annual Dynamic Changes in Lignin Synthesis Metabolites inMetabolites · 2025Article
- Integrated metabolome and transcriptome analysis of maize roots response to different degrees of drought stress.BMC plant biology · 2025Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought is a common abiotic stress for terrestrial plants and often affects crop development and yield. Recent studies have suggested that lignin plays a crucial role in plant drought tolerance; however, the underlying molecular mechanisms are still largely unknown. Here, we report that the rice (Oryza sativa) gene CINNAMOYL-CoA REDUCTASE 10 (OsCCR10) is directly activated by the OsNAC5 transcription factor, which mediates drought tolerance through regulating lignin accumulation. CCR is the first committed enzyme in the monolignol synthesis pathway, and the expression of 26 CCR genes was observed to be induced in rice roots under drought. Subcellular localisation assays revealed that OsCCR10 is a catalytically active enzyme that is localised in the cytoplasm. The OsCCR10 transcript levels were found to increase in response to abiotic stresses, such as drought, high salinity, and abscisic acid (ABA), and transcripts were detected in roots at all developmental stages. In vitro enzyme activity and in vivo lignin composition assay suggested that OsCCR10 is involved in H- and G-lignin biosynthesis. Transgenic rice plants overexpressing OsCCR10 showed improved drought tolerance at the vegetative stages of growth, as well as higher photosynthetic efficiency, lower water loss rates, and higher lignin content in roots compared to non-transgenic (NT) controls. In contrast, CRISPR/Cas9-mediated OsCCR10 knock-out mutants exhibited reduced lignin accumulation in roots and less drought tolerance. Notably, transgenic rice plants with root-preferential overexpression of OsCCR10 exhibited higher grain yield than NT controls plants under field drought conditions, indicating that lignin biosynthesis mediated by OsCCR10 contributes to drought tolerance.
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