Evidence map›Paper›PMID 34786764›Full record

ArticleMagnetic resonance in medicine2022

Fundamentals of turbulent flow spectrum imaging.

Hannes Dillinger, Charles McGrath, Christian Guenthner, Sebastian Kozerke

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease.Journal of cardiovascular development and disease · 2023
    Review
  2. Article
  3. Fundamentals of turbulent flow spectrum imaging.Magnetic resonance in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hannes DillingerInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-5597-5273
Charles McGrathInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-3110-4051
Christian GuenthnerInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0001-8707-7016
Sebastian KozerkeInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-3725-8884
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo introduce a mathematical framework and in-silico validation of turbulent flow spectrum imaging (TFSI) of stenotic flow using phase-contrast MRI, evaluate systematic errors in quantitative turbulence parameter estimation, and propose a novel method for probing the Lagrangian velocity spectra of turbulent flows. THEORY AND

methodsThe spectral response of velocity-encoding gradients is derived theoretically and linked to turbulence parameter estimation including the velocity autocorrelation function spectrum. Using a phase-contrast MRI simulation framework, the encoding properties of bipolar gradient waveforms with identical first gradient moments but different duration are investigated on turbulent flow data of defined characteristics as derived from computational fluid dynamics. Based on theoretical insights, an approach using velocity-compensated gradient waveforms is proposed to specifically probe desired ranges of the velocity autocorrelation function spectrum with increased accuracy.

resultsPractical velocity-encoding gradients exhibit limited encoding power of typical turbulent flow spectra, resulting in up to 50% systematic underestimation of intravoxel SD values. Depending on the turbulence level in fluids, the error due to a single encoding gradient spectral response can vary by 20%. When using tailored velocity-compensated gradients, improved quantification of the Lagrangian velocity spectrum on a voxel-by-voxel basis is achieved and used for quantitative correction of intravoxel SD values estimated with velocity-encoding gradients.

conclusionTo address systematic underestimation of turbulence parameters using bipolar velocity-encoding gradients in phase-contrast MRI of stenotic flows with short correlation times, tailored velocity-compensated gradients are proposed to improve quantitative mapping of turbulent blood flow characteristics.

Indexed as

HydrodynamicsMagnetic Resonance ImagingBlood Flow VelocityComputer SimulationConstriction, PathologicHumansphase-contrast MRIpulse sequence designReynolds stress tensorturbulent blood flowturbulent kinetic energy

Identifiers

PMID34786764
PMCPMC9299145
OpenAlexW3213675835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.