Evidence map›Paper›PMID 34786737›Full record

ArticleJournal of medical virology2022

Usefulness of SARS-CoV-2 antigen test sample as input for SARS-CoV-2 RT-PCR analysis.

Cristina García-Salguero, Esther Culebras, Paloma Merino, Elvira Baos, Alberto Delgado-Iribarren

Abstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Cost-effectiveness analysis of COVID-19 tests in the unified health system.Cost effectiveness and resource allocation : C/E · 2023
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina García-SalgueroDepartment of Clinical Microbiology, IML and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.
Esther CulebrasDepartment of Clinical Microbiology, IML and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.
Paloma MerinoDepartment of Clinical Microbiology, IML and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.
Elvira BaosDepartment of Clinical Microbiology, IML and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.
Alberto Delgado-IribarrenDepartment of Clinical Microbiology, IML and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 rapid detection is of great interest to prevent viral dissemination. In that sense, antigen tests appeared as a very valuable tool to reach this goal. However, it is possible to obtain a negative result in those patients with low viral loads, and consequently, reverse transcription-polymerase chain reaction (RT-PCR) should be performed on samples from patients with a negative antigen test in which there is a strong suspicion of COVID infection. The common diagnostic algorithm involves taking a second sample for RT-PCR testing. This study evaluates the usefulness of the antigen test sample for carrying out RT-PCR analysis when necessary. Results obtained indicate that can be used a unique sample for both antigen test and RT-PCR. This data showed that it is possible to reduce excessive suspected individuals managing and so on increase staff security and patient comfort.

Indexed as

COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingCOVID-19HumansSARS-CoV-2Sensitivity and SpecificitySpecimen HandlingViral Loadantigen testCOVID-19RT-PCRSARS-CoV-2

Identifiers

PMID34786737
PMCPMC8661811

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.