Evidence map›Paper›PMID 34786590›Full record

ArticlePharmacoEconomics2022

The EQ-5D-5L Valuation Study in Egypt.

Sahar Al Shabasy, Maggie Abbassi, Aureliano Finch, Bram Roudijk, Darrin Baines, Samar Farid

Registry-linked trialAbstract read
In one paragraph

Article in PharmacoEconomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05993871 (Diabetic Small Fiber Neuropathy), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05993871 completednot on this mapstarted 2023, after this paper: background citation

Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study

TypeobservationalSponsorTanta UniversityRan2023 to 2024Enrolled45ConditionsSmall Fiber Neuropathy, Diabetic Neuropathies, Autonomic Neuropathy, Diabetic Peripheral NeuropathyArmsClinical Evaluation/Questionnaires, Nerve Conduction Study, Small fiber electrodiagnostic tests, Nerve Ultrasound, Skin Biopsy
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. The EQ-5D-5L valuation study in Nigeria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  7. Article
  8. Factors associated with health state valuations: a secondary analysis of an EQ-5D-3L valuation study from Jordan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  9. Validation of the Arabic version of the composite autonomic symptom score 31 questionnaire in diabetic autonomic neuropathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. EQ-5D-5L Iranian population norms derived from the local value set during the COVID-19 pandemic.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  15. Article
  16. Valuing health-related quality of life: an EQ-5D-5L value set for Morocco.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  17. Comparison of four approaches in eliciting health state utilities with SF-6Dv2.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  18. Valuation of the EQ-5D-3L in Jordan.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sahar Al ShabasyDepartment of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.
Maggie AbbassiDepartment of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.
Aureliano FinchEuroQol Group Office, Rotterdam, The Netherlands.
Bram RoudijkEuroQol Group Office, Rotterdam, The Netherlands.
Darrin BainesInitiate Consultancy, London, UK.
Samar FaridDepartment of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. samar.farid@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-6048-847X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNo value sets exist for either the EQ-5D-3L or the EQ-5D-5L in Egypt, despite local pharmacoeconomic guidelines recommending the use of the EQ-5D to derive utility. Most published Egyptian economic evaluation studies have used utility values from other published studies and systematic reviews.

objectiveOur objective was to develop an Egyptian EQ-5D-5L value set using the international EuroQol standardized protocol (EQ-VT-2.1). This study is a revision of a previous EQ-5D-5L value set for Egypt retracted by the authors.

methodsAdult Egyptian participants were recruited from public places using multi-stratified quota sampling based on age, sex, and geographical distribution. Two elicitation techniques were applied: the composite time trade-off (cTTO) and discrete-choice experiments (DCEs). Before actual data collection, interviewers' performance was assessed in a pilot phase. Data were modelled using generalized least squares, Tobit, heteroskedastic, logit, and hybrid models, and the best fitting model was selected based on logical consistency of the parameters, significance level, prediction accuracy, and model parsimony.

resultsA total of 1378 interviews were conducted, of which 188 were excluded because they were incomplete and did not comply with the protocol, 216 were pilot interviews, and 974 were included in the final analysis. The heteroskedastic model with constraints (model 4) based on the cTTO data was selected as the preferred model to generate the value set. Values ranged from - 0.964 for the worst health state (55555) to 1 for full health (11111) and 0.948 for 11211, with 1123 of all predicted health states (35.94%) being worse than dead. Mobility had the largest impact on health state preference values.

conclusionThis is the first value set for the EQ-5D-5L based on social preferences obtained from a nationally representative sample in Egypt or any Arabic-speaking country. The value set can be used as a scoring system for economic evaluation and to improve the quality of health technology assessment in the Egyptian healthcare system.

Indexed as

Health StatusQuality of LifeAdultCost-Benefit AnalysisEgyptHumansSurveys and Questionnaires

Identifiers

PMID34786590
PMCPMC8595057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.