Evidence map›Paper›PMID 34786498›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2021

Alterations of endotoxin distribution across different biofluids and relevant inflammatory responses by supplementing L-theanine in dairy cows during heat stress.

Zuo Wang, Lingmei Zhang, Zhicai Li, Yuannian Yu, Lingyuan Yang, Peihua Zhang, Weijun Shen, Fachun Wan, Jianhua He, Wenjun Xiao and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. DietaryAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. L-Theanine and Immunity: A Review.Molecules (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Dietary Supplementation of Enzymatically TreatedFrontiers in veterinary science · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zuo WangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Lingmei ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Zhicai LiDeren Dairy Co. Ltd., Changde, Hunan, 415921, China.
Yuannian YuCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Lingyuan YangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Peihua ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Weijun ShenCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Fachun WanCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Jianhua HeCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Wenjun XiaoCollege of Horticulture, Hunan Agricultural University, Changsha, Hunan, 410128, China.
Dasheng YangKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, 410125, China.
Zhiliang TanKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, 410125, China.
Shaoxun TangKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, 410125, China.
Hunan Agricultural University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present trial was performed to reveal the regulatory effects of L-theanine on the levels of lipopolysaccharide (LPS) endotoxin within different biofluids, as well as relevant inflammatory responses of dairy cattle under heat stress conditions. Thirty lactating Chinese Holstein dairy cattle (189 ± 47 days in milk, and 2 ± 1 parities) were allocated in a completely randomized design to each of 3 dietary treatments: the control (CON, 0 g/d per cow L-theanine), the low L-theanine dosage treatment (LL, 16 g/d per cow L-theanine), and the high L-theanine dosage treatment (HL, 32 g/d per cow L-theanine). This trial consisted of 38 d (7 d for adaption and 31 d for data and sample collection), and sample collection for rumen liquid, blood plasma or serum, and milk were conducted on the d 27 and 38, respectively. Dairy cattle were constantly exposed to environmental heat stress during this experiment according to the recorded temperature-humidity index (THI). In the LL treatment, LPS concentration in rumen liquid was higher (

Indexed as

EndotoxinHeat stressInflammationL-theanine

Identifiers

PMID34786498
PMCPMC8566959
OpenAlexW3200477126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.