ArticleNeurobiology of stress2021
Sex differences in the association between basal serum cortisol concentrations and cortical thickness.
Article in Neurobiology of stress, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 13 citations in OpenAlex.
- Long-term effect of early-life arsenic exposure on morning plasma cortisol in adults from Antofagasta, Chile.Environmental health : a global access science source · 2026Article
- From shared mechanisms to treatment gaps: a review of the comorbidity between eating disorders and PTSD.Journal of eating disorders · 2025Review
- Long-Term Effect of Early-Life Arsenic Exposure on Morning Plasma Cortisol in Adults from Antofagasta, Chile.medRxiv : the preprint server for health sciences · 2025Article
- Increased Salt-Sensitive Blood Pressure in Women vs Men: Is Relative Hyperaldosteronism the Mechanism?The Journal of clinical endocrinology and metabolism · 2025Article
- Differences in bone turnover markers and injury risks between local and international horses: A Victorian Spring Racing Carnival study.Equine veterinary journal · 2025Article
- The impact of extinction timing on pre-extinction arousal and subsequent return of fear.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Establishing Reference Intervals for Serum and Salivary Cortisol in a Selected Population in Kano, Nigeria.Annals of clinical and laboratory science · 2024Article
- Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.International journal of molecular sciences · 2024Article
- Temporal Interactions between Maintenance of Cerebral Cortex Thickness and Physical Activity from an Individual Person Micro-Longitudinal Perspective and Implications for Precision Medicine.Journal of personalized medicine · 2024Article
- Socioeconomic Disparities in Hypothalamic-Pituitary-Adrenal Axis Regulation and Prefrontal Cortical Structure.Biological psychiatry global open science · 2024Review
- Sex Determines Anterior Cingulate Cortex Cortical Thickness in the Course of Depression.Biological psychiatry global open science · 2024Article
- Association between childhood maltreatment and adult cortisol concentrations mediated through subjective health complaints.Frontiers in epidemiology · 2023Article
- Cortisol and periodontitis: Prospective observational and Mendelian randomization studies.Frontiers in endocrinology · 2023Observational
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBasal cortisol concentrations vary between men and women. Likewise, previous findings suggest stress-related cortical thickness alterations. Thus, we aimed at elucidating sex differences in the association between serum cortisol concentrations and cortical thickness.
methodsData of 2594 participants (55.55% male; mean age = 53.55 years ± 13.17 years) of the general population were used to investigate sex differences in basal serum cortisol concentrations and associations of serum cortisol concentrations with global and regional cortical thickness. The validity of the results was tested by including sex hormone concentrations as a biological and childhood maltreatment and depressive symptoms as a psychological confounder.
resultsBasal serum cortisol concentrations were higher in men than in women (β = -0.158, t
conclusionSex differences in serum cortisol concentrations and the association between serum cortisol concentrations and cortical thickness suggest important sex-specific effects of stress on the brain. Future studies should integrate the interaction between the hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis in sex-stratified analyses.
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