Evidence map›Paper›PMID 34786440›Full record

ArticleNeurobiology of stress2021

A voxel-level brain-wide association study of cortisol at 8 a.m.: Evidence from Cushing's disease.

Yanyang Zhang, Tao Zhou, Shiyu Feng, Xinyun Liu, Fuyu Wang, Zhiqiang Sha, Xinguang Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of stress, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yanyang ZhangDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Tao ZhouDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Shiyu FengDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Xinyun LiuDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Fuyu WangDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Zhiqiang ShaDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Xinguang YuDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China.
Chinese PLA General Hospital · CNUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cortisol, the end product of the hypothalamic-pituitary-adrenal axis, regulates cognitive function and emotion processing. Cushing's disease, which is characterized by a unique excess of cortisol upon clinical diagnosis, serve as an excellent

Indexed as

CognitionConnectivityCortisolFunctional magnetic resonance imagingGene expression

Identifiers

PMID34786440
PMCPMC8578035
OpenAlexW3210249452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.