Evidence map›Paper›PMID 34786434›Full record

ArticleMolecular therapy. Methods & clinical development2021

Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues.

Anita Badbaran, Reiner K Mailer, Christine Dahlke, Jannis Woens, Anahita Fathi, Sibylle C Mellinghoff, Thomas Renné, Marylyn M Addo, Kristoffer Riecken, Boris Fehse

Abstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anita BadbaranDepartment of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246 Hamburg, Germany.
Reiner K MailerInstitute of Clinical Chemistry and Laboratory Medicine, UKE, 20246 Hamburg, Germany.
Christine DahlkeDivision of Infectious Diseases, 1st Department of Medicine, UKE, 20246 Hamburg, Germany.
Jannis WoensDepartment of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246 Hamburg, Germany.
Anahita FathiDivision of Infectious Diseases, 1st Department of Medicine, UKE, 20246 Hamburg, Germany.
Sibylle C MellinghoffDivision of Infectious Diseases, 1st Department of Medicine, UKE, 20246 Hamburg, Germany.
Thomas RennéInstitute of Clinical Chemistry and Laboratory Medicine, UKE, 20246 Hamburg, Germany.
Marylyn M AddoDivision of Infectious Diseases, 1st Department of Medicine, UKE, 20246 Hamburg, Germany.
Kristoffer RieckenDepartment of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246 Hamburg, Germany.
Boris FehseDepartment of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246 Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination with the adenoviral-vector-based AstraZeneca ChAdOx1 nCov-19 (Vaxzevria) vaccine is efficient and safe. However, in rare cases vaccinated individuals developed life-threatening thrombotic complications, including thrombosis in cerebral sinus and splanchnic veins. Monitoring of the applied vector

Indexed as

adenoviral vectorAZD1222ChAdOx1 nCoV-19digital PCRSARS-Cov2vaccinationvaccine-induced immune thrombotic thrombocytopenia (VITT)Vaxzevria

Identifiers

PMID34786434
PMCPMC8566940

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.