ArticleWorld journal of clinical cases2021
Skeletal muscle metastasis with bone metaplasia from colon cancer: A case report and review of the literature.
Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Skeletal Muscle Metastases from Colorectal Adenocarcinoma: A Rare Case Report with Literature Review.Reports (MDPI) · 2026Article
- Case Report: A rare solitary peroneus longus metastasis from rectal cancer managed with multimodal therapy.Frontiers in medicine · 2026Article
- Soft tissue metastasis in colorectal cancer: a case report.Journal of medical case reports · 2025Article
- Gefitinib induces apoptosis in Caco-2 cells via ER stress-mediated mitochondrial pathways and the IRE1α/JNK/p38 MAPK signaling axis.Medical oncology (Northwood, London, England) · 2025Article
- 18F-FDG PET/CT imaging of several asymptomatic skeletal muscle metastases of mixed germ cell ovarian cancer.Clinical case reports · 2023Article
- Ossifying skeletal muscle metastasis as an initial manifestation of colorectal adenocarcinoma.Radiology case reports · 2023Article
- Skeletal muscle metastasis from colorectal adenocarcinoma: A literature review.World journal of gastrointestinal surgery · 2022Article
- Machine learning algorithms to predict atypical metastasis of colorectal cancer patients after surgical resection.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColon cancer is a common malignant disease of the gastrointestinal tract and usually occurs at the junction of the rectum and sigmoid colon. Lymphatic and hematogenous metastases occur frequently in colon cancer and the most common metastatic sites include the liver, lung, peritoneum, bone, and lymph nodes. As a manifestation of advanced tumor spread and metastasis, soft tissue metastasis, especially skeletal muscle metastasis with bone metaplasia caused by colon cancer, is rare, accounting for less than 1% of metastases. CASE SUMMARY: A 43-year-old male patient developed skeletal muscle metastasis with bone metaplasia of the right proximal thigh 5 mo after colon cancer was diagnosed. The patient was admitted to the hospital because of pain caused by a local mass on his right thigh. Positron emission tomography-computed tomography showed many enlarged lymph nodes around the abdominal aorta but no signs of lung or liver metastases. Color ultrasound revealed a mass located in the skeletal muscle and the results of histological biopsy revealed a poorly differentiated adenocarcinoma suspected to be distant metastases from colon cancer. Immunohistochemistry showed small woven bone components that were considered to be ossified.
conclusionThis case reminds us that for patients with advanced colorectal tumors, we should be alert to the possibility of unconventional metastasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.