Evidence map›Paper›PMID 34786403›Full record

ArticleWorld journal of clinical cases2021

Rapid progression of colonic mucinous adenocarcinoma with immunosuppressive condition: A case report and review of literature.

Youhei Koseki, Kenya Kamimura, Yuto Tanaka, Marina Ohkoshi-Yamada, Qiliang Zhou, Yoshifumi Matsumoto, Takeshi Mizusawa, Hiroki Sato, Akira Sakamaki, Hajime Umezu and 2 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Youhei KosekiDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Kenya KamimuraDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Yuto TanakaDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Marina Ohkoshi-YamadaDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Qiliang ZhouDepartment of Medical Oncology, Niigata University, Niigata 9518510, Japan.
Yoshifumi MatsumotoDepartment of Medical Oncology, Niigata University, Niigata 9518510, Japan.
Takeshi MizusawaDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Hiroki SatoDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Akira SakamakiDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Hajime UmezuDivision of Pathology, Niigata University, Niigata 9518510, Japan.
Junji YokoyamaDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Shuji TeraiDivision of Gastroenterology and Hepatology, Niigata University, Niigata 9518510, Japan.
Niigata University of Rehabilitation · JPNiigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal mucinous adenocarcinoma is a rare subtype of colorectal cancer and is characterized by an abundance of mucin in the tumor. In addition, the colorectal mucinous adenocarcinoma often demonstrates poor differentiation in the histology of tumor cells and poor prognosis compared with those with adenocarcinoma. Here, we present the case of a young woman with colonic mucinous adenocarcinoma showing significantly rapid progression within four months of immunosuppressant therapy for Henoch-Schönlein purpura. CASE SUMMARY: Here we report a rare case of ascending colon mucinous adenocarcinoma with lymph node and liver metastases which developed and progressed rapidly within four months during the treatment of Henoch-Schönlein purpura using corticosteroids. The systemic screening examinations showed no tumors before the immunosuppressant therapy. Fortunately, the patient was successfully treated with chemotherapy.

conclusionWhile no direct evidence that the immunosuppressants accelerated the tumor development, the case presenta tion and review of the literature demonstrated that surveillance for malignancies before and during treatment with immunosuppressive agents is essential.

Indexed as

Case reportColorectal cancerCorticosteroidImmunosuppressantMucinous carcinoma

Identifiers

PMID34786403
PMCPMC8567511
OpenAlexW3207511174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.