A case of von Hippel-Lindau disease with renal cell carcinoma treated by partial nephrectomy with pre- and post-surgical axitinib therapy.

Takahiro Akioka, Naoki Terada, Hiroki Takamori, Toshio Kamimura, Shoichiro Mukai, Toshiyuki Kamoto

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Article in Urology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 78% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

Diabetic ketoacidosis associated with pancreatic involvement in a patient with von Hippel-Lindau syndrome: a case report.Frontiers in endocrinology · 2026
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5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Takahiro AkiokaDepartment of Urology, Miyazaki University, Miyazaki, Japan.

Naoki TeradaDepartment of Urology, Miyazaki University, Miyazaki, Japan.

Hiroki TakamoriDepartment of Urology, Miyazaki University, Miyazaki, Japan.

Toshio KamimuraDepartment of Urology, Miyazaki University, Miyazaki, Japan.

Shoichiro MukaiDepartment of Urology, Miyazaki University, Miyazaki, Japan.

Toshiyuki KamotoDepartment of Urology, Miyazaki University, Miyazaki, Japan.

University of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary disease with benign and malignant tumors occurring in various organs including the kidneys. In patients with renal cell carcinoma (RCC) lesions in both kidneys, it is difficult to determine the treatment strategy. We report a case of VHL disease with RCC treated via partial nephrectomy after 6 months of axitinib therapy. Then, the patient continued to receive low-dose axitinib therapy without any signs of tumor progression for 3 years after surgery. Axitinib combined with surgery might be a treatment option for patients with VHL disease harboring bilateral RCC.

Indexed as

AxitinibPartial nephrectomyRenal cell carcinomaVon hippel-lindau disease

Identifiers

PMID34786348

DOI10.1016/j.eucr.2021.101925

PMCPMC8579142

OpenAlexW3208779629

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.