ArticleAmerican journal of translational research2021
Effect of dexmedetomidine combined with propofol on stress response, hemodynamics, and postoperative complications in patients undergoing laparoscopic cholecystectomy.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Outcomes of dexmedetomidine as adjuvant drug in patients undergoing videolaparoscopic cholecystectomy: A randomized and prospective clinical trial.International journal of immunopathology and pharmacologyTrial
- Study on the mechanism of Dexmedetomidine's effect on postoperative cognitive dysfunction in elderly people.Frontiers in physiology · 2025Review
- Efficacy of dexmedetomidine epidural anesthesia combined with nano-silver polyurethane dressing in gynecological surgery and its influence on hemodynamics, inflammatory response and postoperative recovery.American journal of translational research · 2024Article
- Influences of dexmedetomidine on stress responses and postoperative cognitive and coagulation functions in patients undergoing radical gastrectomy under general anesthesia.World journal of gastrointestinal surgery · 2023Article
- Effects of Dexmedetomidine on Immunomodulation and Pain Control in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis research was designed to probe the effect of dexmedetomidine combined with propofol on stress response, hemodynamics, and postoperative complications in patients undergoing laparoscopic cholecystectomy.
methodsAltogether 144 patients who underwent laparoscopic cholecystectomy in the Beibei Traditional Chinese Medical Hospital, the Sixth People's Hospital of Chongqing from January 2018 to July 2020 were research subjects. The control group (CG) (n=68) received propofol continuous pumping sedation, while the research group (RG) (n=76) was given dexmedetomidine combined with propofol continuous pumping sedation. The quality of postoperative recovery and incidence of postoperative complications of the two groups were observed and compared. The hemodynamic indexes (HR, SpO
resultsCompared with the CG, the incidence of postoperative complications in the RG was lower, and the quality of postoperative recovery (time of breathing recovery, eye opening, consciousness and extubation) was better. Besides, the hemodynamic indexes of the RG were more stable, and the levels of stress indexes Cortisol, ACTH, and NE were lower. The RG had VAS and SAS scores that were lower, and MMSE scores were higher.
conclusionDexmedetomidine combined with propofol can effectively alleviate the stress response of patients undergoing laparoscopic cholecystectomy, stabilize perioperative hemodynamics, and reduce postoperative complications.
Indexed as
Identifiers
34786111PMC8581921W3213479841What OpenQuestion holds
Registered trials
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